GLP-Complete: 3-Step System for Natural GLP-1 Pathway Support & Metabolic Balance
3-step daily system supporting GLP-1, gut health, and metabolism. · $119.99 or $101.99/mo
L-Methylfolate (1mg) Plus Methyl-B12*
The body-ready folate + B12 formula for mood, methylation, and brain health.
- No conversion required — 5-MTHF is immediately absorbed without the metabolic processing steps that synthetic folic acid demands*
- Supports mood, energy, and mental clarity — fuels neurotransmitter production for serotonin, dopamine, and norepinephrine*
- Paired with Methyl B12 for complete methylation support — L-Methylfolate can't do its job without B12*
1 fl oz · 300 Servings
Supplement Facts
- Folate
- Vitamin B12
HSA/FSA Eligible
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L-Methylfolate (1mg) Plus Methyl-B12*
HSA/FSA Eligible
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- Absorbs directly into the bloodstream and requires no processing from the body.
- Contains the essential Cofactor MethylB12.
- Supports brain and heart health and contributes to balancing energy, hormones, and mood
L-Methylfolate is the biologically active, bloodstream-ready form of Folate (Vitamin B9). Our formulation provides a daily dose of 1 mg L-Methylfolate. This strength was formulated to support everyday Folate nutritional needs. The formula also includes a whole serving of Methyl-B12, an essential cofactor to L-Methylfolate. The liquid sublingual form provides enhanced absorption and an enjoyable cherry flavor. It also contributes to the production of neurotransmitters, which are involved in maintaining focus, regulating sleep patterns, providing energy, balancing hormones, and impacting mood. Furthermore, Methylfolate promotes heart health and optimal nerve function.*
- Supports mood & cognition*
Supports healthy methylation*
Supports heart health*
Supports nerve cognition*
- Folate
- Vitamin B12
Shake before use. Add 2 droplets on or under the tongue. Drops can also be added to water, juice, or smoothie.
Available strengths & formulations
Kids Methylfolate Plus B12 Cofactor
$22.95
or $19.51/mo
ADDED
Flavor:
L-Methylfolate (1 mg) Plus Methyl B12 Capsules
$17.99
or $15.29/mo
ADDED
L-Methylfolate (15 mg) Plus Methyl B12 Capsules
$22.99
or $19.54/mo
ADDED
L-Methylfolate (15 mg) Plus Methyl-B12
$22.99
or $19.54/mo
ADDED
L-Methylfolate (1mg) Plus Methyl-B12
$24
or $20.40/mo
ADDED
L-Methylfolate (7.5 mg) Plus Methyl B12 Capsules
$20.99
or $17.84/mo
ADDED
L-Methylfolate (7.5mg) Plus Methyl-B12
$18.99
or $16.14/mo
ADDED
See how L-Methylfolate helped others
Healthy methylation plays a role in many everyday functions:
Mental
clarity*
Emotional
balance*
Cellular energy
production*
Healthy
hair*
Skin
health*
Energy
metabolism*
Emotional
well-being*
Stress
response*
Supports
heart health*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
How L-Methylfolate works in the body
-
Supports neurotransmitters like serotonin, dopamine & norepinephrine.*
-
Supports red blood cells production and detox in the body.*
-
Helps your homocysteine levels stay in check which is vital for heart and brain health.*
Results Over Time
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Hear From Our Experts
"As a health researcher, I view L-Methylfolate as an essential nutrient for neurological, emotional, and metabolic balance—especially in individuals with genetic variants like MTHFR. Triquetra’s L-Methylfolate line stands out for its clinically relevant dosing, exceptional purity, and highly bioavailable formulas, with options tailored for both adults and children. It’s a science-backed choice for those seeking therapeutic efficacy and uncompromising quality."
- Adriano Zanardi da Silva, M.Sc., Ph.D
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
How to take L-Methyfolate
1. Shake well before use.
2. Take 2 droplets directly under tongue OR mix 2 droplets into your favorite drinks, smoothies or water.
Which dose is right for you?
1mg light supplementation
Starting dose for general wellness or anyone new to methylated folate
7.5mg moderate supplementation
For those supporting folate metabolism and cellular function at a higher level*
15mg high therapeutic use
For advanced nutritional needs or personalized wellness goals under healthcare guidance*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Standards Without Compromise
This formula is crafted with thoughtfully selected ingredients and manufactured to rigorous quality standards.
GMO
Free
Vegan
Gluten
Free
Thoughtfully formulated. Independently tested.
We prioritize transparent sourcing, thoughtful formulation, and third-party testing standards to help ensure quality, purity, and consistency across our products.
Third-Party Tested
Products are independently tested to verify quality, purity, potency, and ingredient standards.
Thoughtfully Sourced Ingredients
We partner with trusted suppliers to select premium ingredients backed by research and rigorous quality standards.
Intentional Formulations
Every formula is designed for ingredient compatibility, bioavailability, and effective dosing.
GMP-Certified Manufacturing
Manufactured in GMP-certified facilities that follow established quality control standards.
Third-Party Tested
GMP-Certified Facility
Transparent Sourcing
Practitioner-Informed
Quality-Focused
Frequently asked questions
L-Methylfolate is the active form of folate that your body can use immediately. Folic acid needs to be converted—and some people can’t do that well because of genetic mutations like MTHFR.
Methyl B12 (aka Methylcobalamin) is a highly bioavailable form of B12 that works synergistically with L-Methylfolate to support brain health, energy, and mood.
Check with your doctor first.
It is possible L-Methylfolate may interact with certain medications. It is always best to check with a healthcare provider before starting any supplements.
Most people tolerate it well. If you feel like you are sensitive to higher doses, you can work your way up to the full dose over time.
It can be taken with or without food, but some people prefer it with a meal to avoid mild stomach discomfort.
Build Your Complete Routine
Warning: If you have a medical condition or are taking medication, contact a physician before taking this supplement. Keep out of reach of children. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
To report a serious adverse event, please contact 844-272-6337.
