L-Methylfolate (1 mg) Plus Methyl B12 Capsules

Triquetra L-Methylfolate 1 mg capsules with 5-MTHF active folate and methyl B12 for methylation, brain, mood, heart and nerve support

Woman holding Triquetra L-Methylfolate 1 mg capsules with 5-MTHF folate and methyl B12 for methylation and cellular health support

Triquetra L-Methylfolate 1 mg capsules with 5-MTHF active folate and 500 mcg methyl B12 clinically validated dose for methylation support

L-Methylfolate 1 mg capsules with 5-MTHF folate and methyl B12 supporting mood, cognition, methylation, heart health and nerve function

L-Methylfolate 5-MTHF bioactive folate with methyl B12 capsules supporting methylation, homocysteine metabolism and nutrient absorption

Supplement facts label for Triquetra L-Methylfolate 1 mg capsules with 5-MTHF folate and 500 mcg methyl B12 plus vegan and GMP quality standards

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L-Methylfolate (1 mg) Plus Methyl B12 Capsules

Key Ingredients

Folate
Vitamin B12

Size / Suggested Use

Size: 60 Capsules - 60 Servings

Product Details

L-Methylfolate is a bioactive form of folate (B9) that requires fewer metabolic conversion steps in the body. This can help support efficient absorption and utilization. Formulated with Methylcobalamin B12 to help maintain healthy homocysteine metabolism, support normal nerve function, and promote cardiovascular well-being by aiding natural nitric oxide pathways.*

A high-quality supplement formulated to help support a positive mood, promote healthy energy levels, enhance mental clarity, and encourage restful sleep.*

Our high-quality L-Methylfolate and Methyl B12 supplement is formulated based on clinical research to support healthy methylation. Each capsule provides 1 mg of L-Methylfolate (5-MTHF) plus 500 mcg of Methyl B12. L-Methylfolate is a biologically active form of folate that requires minimal conversion by the body. This formulation is designed to help support a healthy mood and brain function.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Supplement Facts

Healthy methylation plays a role in many everyday functions:

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Methylated Folate: A Nutrient Form Some People Prefer for Genetic Support*

Certain MTHFR gene variations may affect how the body processes synthetic folic acid. Methylated forms like 5-MTHF can offer a more direct form of folate support.

Methylated vitamins provide folate in a body-ready form, supporting bioavailability and cellular use.*

Up to 40% of people may carry a common MTHFR gene variant.*

How L-Methylfolate Works in the Body

Supports neurotransmitters like serotonin, dopamine & norepinephrine.*

Supports red blood cells production and detox in the body.*

Helps your homocysteine levels stay in check which is vital for heart and brain health.*

Clinically Validated Doses

1mg L-Methylfolate

L-Methylfolate is the active & bloodstream ready form of Folate (B9) immediately absorbed into the bloodstream without requiring processing by the body.

500mcg Methyl B12

L-Methyfolate cannot do its job in the body without Methyl B12. If L-Methyfolate is the fire, think of Methyl B12 as the firewood.

Reasons to Love Our L-Methylfolate

Designed for Efficient Absorption*

No Conversion Required - Body-Ready Form*

Enhanced with B12*

See how L-Methylfolate Helped Others!

* These testimonials represent individual experiences. Participants received free product samples and were compensated for their time, but their opinions are entirely their own and were not influenced by our team. Individual results may vary.

Body-Ready Nutrients in One Easy Dose

Supports Mood & Cognition*

Supports Healthy Methylation*

Supports Heart Health*

Supports Nerve Cognition*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Which dose is right for you?

1 mg Light

Supplementation

Best For: This is a starting dose for general wellness or individuals who want to support methylation.

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7.5 mg Moderate Supplementation

Best For: Individuals seeking a higher level of methylated folate to support folate metabolism and cellular function.*

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15 mg High

Therapeutic Use

Best For: Those looking for a higher dose of folate to support advanced nutritional needs or personalized wellness goals, as recommended by a healthcare professional.*

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Genetic Wellness Support Starts Early

Daily Nutritional Folate support with

KIDS L-Methylfolate

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Results Over Time

3-7 Days: Gradual Support*

Some individuals may begin to notice support for mental clarity, mood balance, and energy. This is also when nutritional support for red blood cell formation and homocysteine metabolism may begin.*

Weeks 4-8: Noticeable Support*

Neurotransmitter production for the ‘feel good’ hormones like serotonin & dopamine goes up which can help with an improvement in mood and a reduction in symptoms of anxiety.*

Month 3-6: Ongoing Support*

Some individuals may notice more consistent energy levels and support for healthy eating patterns. Users have also shared feeling more in tune with their overall wellness goals and daily routines.*

Disclaimer: Individual results vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Hear From Our Experts

"As a health researcher, I view L-Methylfolate as an essential nutrient for neurological, emotional, and metabolic balance—especially in individuals with genetic variants like MTHFR. Triquetra’s L-Methylfolate line stands out for its clinically relevant dosing, exceptional purity, and highly bioavailable formulas, with options tailored for both adults and children. It’s a science-backed choice for those seeking therapeutic efficacy and uncompromising quality."

Adriano Zanardi da Silva, M.Sc., Ph.D

Quality Standards You Can Trust

Warning: If you have a medical condition or are taking medication, contact a physician before taking this supplement. Keep out of reach of children.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

To report a serious adverse event, please contact 844-272-6337.

Frequently Asked Questions

What is L-Methylfolate and how is it different from folic acid?

L-Methylfolate is the active form of folate that your body can use immediately. Folic acid needs to be converted—and some people can’t do that well because of genetic mutations like MTHFR.

What is Methyl B12 and why is it paired with L-Methylfolate?

Methyl B12 (aka Methylcobalamin) is a highly bioavailable form of B12 that works synergistically with L-Methylfolate to support brain health, energy, and mood.

Is this product safe if I’m pregnant or breastfeeding?

Check with your doctor first. L-Methylfolate is often recommended during pregnancy, but always confirm with your healthcare provider.

Can this supplement interact with medications?

It is possible L-Methylfolate may interact with certain medications. It is always best to check with a healthcare provider before starting any supplements.

Are there any known side effects?

Most people tolerate it well. If you feel like you are sensitive to higher doses, you can work your way up to the full dose over time.

How do I take it — with food or without?

It can be taken with or without food, but some people prefer it with a meal to avoid mild stomach discomfort.

Love this stuff

Day one I had an extreme energy and mood boost then it evend out. Without divulging personal information all I can say is I feel much more like myself since starting this stuff. I have noticed a huge improvement in my mood, energy, even my cognitive improvement. This is better than any medication I have ever been prescribed.

Great service

They are so cordial and want to keep customers satisfied! This is awesome 🤩

Good product

Very good product!

L-Methylfolate (1 mg) Plus Methyl B12 Capsules

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Key Ingredients

Size / Suggested Use

Product Details

Supplement Facts

Select Your Plan

How L-Methylfolate Works in the Body

Clinically Validated Doses

Reasons to Love Our L-Methylfolate

See how L-Methylfolate Helped Others!

* These testimonials represent individual experiences. Participants received free product samples and were compensated for their time, but their opinions are entirely their own and were not influenced by our team. Individual results may vary.

Body-Ready Nutrients in One Easy Dose

Which dose is right for you?

3-7 Days: Gradual Support*

Weeks 4-8: Noticeable Support*

Month 3-6: Ongoing Support*

Hear From Our Experts

Quality Standards You Can Trust

Frequently Asked Questions

What is L-Methylfolate and how is it different from folic acid?

What is Methyl B12 and why is it paired with L-Methylfolate?

Is this product safe if I’m pregnant or breastfeeding?

Can this supplement interact with medications?

Are there any known side effects?

How do I take it — with food or without?

Customer Reviews

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