WELLNESS WITHOUT COMPROMISE

Better health, starting daily.

Thoughtfully formulated supplements designed to support whole-body wellness–at doses the research actually used.

Trusted by 3.5M+ customers
SHOP BEST SELLERS WHY TRIQUETRA

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The formulas people come back for.

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CLINICIANS' CHOICE

1,863 clinicians share this on FrontrowMD without compensation.

America’s #1
Methylated
Supplement

Body-ready L-Methylfolate + Methyl B12 formulated to support healthy methylation, cognitive function, mood, and daily energy.

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Rigor At Every Step

From research and sourcing to testing and final release, every product follows a rigorous quality process.

  • Research & Formulation

    Every product begins with scientific research. We select clinically studied ingredients and formulate at meaningful, effective doses.

  • Ingredient Sourcing

    We partner with trusted suppliers and prioritize high-quality, traceable ingredients that meet strict purity standards.

  • Manufacturing

    Products are produced in FDA-registered, cGMP-certified facilities using validated manufacturing processes.

  • In-Process Verification

    Throughout production, ingredients and formulations are checked to ensure accuracy, consistency, and label claim compliance.

  • Third-Party Testing

    Independent laboratories verify identity, potency, heavy metals, and microbial contaminants.

  • Finished Product Release

    Only products that meet our quality standards are approved for distribution and delivered to customers.

Formulated with Doctors. Backed by Research.

Our Science Advisory Board brings research, performance science, and nutritional biochemistry expertise to every formula - grounded in published research.

  • Dr. Will Aguila, M.D.

    Specialist in metabolic health, weight management, and long-term wellness.

  • Dr. Dan Sullivan, ND, IFMCP

    Functional medicine practitioner focused on root-cause health and performance optimization.

  • Dr. Nicole Avena, PhD

    Neuroscientist and nutrition researcher specializing in metabolism and eating behavior.

Why Thousands Trust Triquetra

  • Verified Purchase

    Life changer!!

    I’ve been using this product for over a year and a half and it has literally changed my health in SO MANY WAYS!!!

    Debbie T. 
    Flora Biome
  • Verified Purchase

    Noticed a difference immediately.

    Bought this for my neurodivergent son who has been really struggling, finally noticing a big difference in him ... calmer, less reactive. He said that he felt like school was easier to handle right away ... that his brain could focus!

    Courtney T. 
    L-Methylfolate
  • Verified Purchase

    Your nose will thank you!

    Hands down the BEST nasal spray!! You won't be disappointed!

    Ahndrea R.
    Nasomin

Individual results vary. *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Results Don't Come From One Bottle

Consistency is what makes the research real. Subscribe and finish what you start.

  • Save 15% on every order

    Applied automatically to every subscription order – no codes, every time.

  • Free shipping, delivered on your schedule

    Free shipping on every subscrpition order. Set your delivery interval and never think about it again.

  • Cancel or skip, anytime

    Manage your subscription via text or in our online portal. If it's not working for you, it's easy to cancel.

Best Sellers

Shop Best Sellers

  • L-Methylfolate (15 mg) Plus Methyl B12 Capsules

    Professional-strength active folate with essential Methyl-B12 cofactor
    $22.99 or $19.54/mo

  • Flora Biome™ Live Probiotic

    3-in-1 fermented blend supporting gut balance and digestive wellness.
    $48.00 or $40.80/mo

  • Nasomin Nasal Cleanse

    The natural nasal iodine spray
    $25.00 or $21.25/mo

  • Kids Methylfolate Plus B12 Cofactor

    Supports nutritional needs of children
    $22.95 or $19.51/mo

  • CranEaze Urinary Tract Support

    Clinically formulated blend supporting urinary tract and bladder health.
    $33.00 or $28.05/mo

  • Creatine Reserve™ Dual Pathway Creatine Complex

    Beyond Creatine. Built for Muscle & Mind.
    $38.99 or $33.14/mo

  • Saw Palmetto Extract with Pumpkin Seed Oil

    Saw Palmetto Extract plus Pumpkin Seed Oil
    $31.97 or $27.17/mo

  • FolinicActive™ Kids Folinic Acid + B12 Drops

    Gentle active folate for growing brains
    $26.69 or $22.69/mo

  • BioBeet Beetroot Extract

    Advanced beetroot formula supporting circulation, endurance, and daily performance.
    $25.00 or $21.25/mo
FAMILY-OWNED SINCE DAY ONE

Meet The Founders

Triquetra was born from a deeply personal experience. After struggling with severe health issues and finding few meaningful answers through conventional approaches, founder Sean Gill became obsessed with the connection between nutrition, nature, and whole-body wellness.

His sister Suzanne was walking her own path at the same time — a years-long journey through gut health and whole-body wellness that shaped her conviction that good health is a birthright, and that caring for it should be an autonomous experience: informed, self-directed, and never dependent on shortcuts.

Together, that became the mission: supplements held to a higher standard — clinically informed ingredients, rigorous testing, and complete transparency, so you can take charge of your own wellness.

DISCOVER OUR STORY