L-Methylfolate (1mg) Plus Methyl-B12

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L-Methylfolate (1mg) Plus Methyl-B12

Key Ingredients

Folate
Vitamin B12

Size / Suggested Use

Size: 1 oz - 300 Servings

Product Details

Absorbs directly into the bloodstream and requires no processing from the body.
Contains the essential Cofactor MethylB12.
Supports brain and heart health and contributes to balancing energy, hormones, and mood

L-Methylfolate is the biologically active, highly bioavailable form of Folate (Vitamin B9). Our formulation provides a daily dose of 1 mg L-Methylfolate. This strength was formulated to support everyday Folate nutritional needs. The formula also includes a whole serving of Methyl-B12, an essential cofactor to L-Methylfolate. The liquid sublingual form provides enhanced absorption and an enjoyable cherry flavor. A daily dose of 1 mg of methylfolate plays a crucial role in supporting the healthy development of your baby during pregnancy. It also contributes to the production of neurotransmitters, which are involved in maintaining focus, regulating sleep patterns, providing energy, balancing hormones, and impacting mood. Furthermore, Methylfolate promotes heart health and optimal nerve function.*

Supplement Facts

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Healthy methylation plays a role in many everyday functions:

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Methylated Folate: A Nutrient Form Some People Prefer for Genetic Support*

Certain MTHFR gene variations may affect how the body processes synthetic folic acid. Methylated forms like 5-MTHF can offer a more direct form of folate support.

Methylated vitamins provide folate in a body-ready form, supporting bioavailability and cellular use.*

Up to 40% of people may carry a common MTHFR gene variant.*

Why You’ll Love Our L-Methylfolate

Bloodstream Ready L-Methyfolate*

Designed for Efficient Absorption*

No Conversion Required - Body-Ready Form*

Enhanced with B12*

How L-Methylfolate Works in the Body

Supports neurotransmitters like serotonin, dopamine & norepinephrine.*

Supports red blood cells production and detox in the body.*

Helps your homocysteine levels stay in check which is vital for heart and brain health.*

Body-Ready Nutrients in One Easy Dose

Supports Mood & Cognition*

Supports Healthy Methylation*

Supports Heart Health*

Supports Nerve Cognition*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See how L-Methylfolate Helped Others!

* These testimonials represent individual experiences. Participants received free product samples and were compensated for their time, but their opinions are entirely their own and were not influenced by our team. Individual results may vary.

How to Take L-Methyfolate

1. Shake well before use.

2. Take 2 droplets directly under tongue

OR mix 2 droplets into your favorite drinks, smoothies or water.

Know your supplement

Our drops are a deep, rich burgundy shade. Please be cautious of counterfeit products that may differ in color or quality. To ensure you receive a genuine product, only purchase from our official websites or stores.

Which dose is right for you?

1 mg Light

Supplementation

Best For: This is a starting dose for general wellness or individuals who want to support methylation.

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7.5 mg Moderate Supplementation

Best For: Individuals seeking a higher level of methylated folate to support folate metabolism and cellular function.*

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15 mg High

Supplementation

Best For: Those looking for a higher dose of folate to support advanced nutritional needs or personalized wellness goals, as recommended by a healthcare professional.*

Learn More

Genetic Wellness Support Starts Early

Daily Nutritional Folate support with

KIDS L-Methylfolate

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Results Over Time

3-7 Days: Gradual Support*

Some individuals may begin to notice support for mental clarity, mood balance, and energy. This is also when nutritional support for red blood cell formation and homocysteine metabolism may begin.*

Weeks 4-8: Noticeable Support*

Neurotransmitter production for the ‘feel good’ hormones like serotonin & dopamine goes up which can help with an improvement in mood and a reduction in symptoms of anxiety.*

Month 3-6: Ongoing Support*

Some individuals may notice more consistent energy levels and support for healthy eating patterns. Users have also shared feeling more in tune with their overall wellness goals and daily routines.*

Disclaimer: Individual results vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Hear From Our Experts

"As a health researcher, I view L-Methylfolate as an essential nutrient for neurological, emotional, and metabolic balance—especially in individuals with genetic variants like MTHFR. Triquetra’s L-Methylfolate line stands out for its clinically relevant dosing, exceptional purity, and highly bioavailable formulas, with options tailored for both adults and children. It’s a science-backed choice for those seeking therapeutic efficacy and uncompromising quality."

Adriano Zanardi da Silva, M.Sc., Ph.D

Quality Standards You Can Trust

Warning: If you have a medical condition or are taking medication, contact a physician before taking this supplement. Keep out of reach of children.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

To report a serious adverse event, please contact 844-272-6337.

Frequently Asked Questions

What is L-Methylfolate and how is it different from folic acid?

L-Methylfolate is the active form of folate that your body can use immediately. Folic acid needs to be converted—and some people can’t do that well because of genetic mutations like MTHFR.

What is Methyl B12 and why is it paired with L-Methylfolate?

Methyl B12 (aka Methylcobalamin) is a highly bioavailable form of B12 that works synergistically with L-Methylfolate to support brain health, energy, and mood.

Is this product safe if I’m pregnant or breastfeeding?

Check with your doctor first. L-Methylfolate is often recommended during pregnancy, but always confirm with your healthcare provider.

Can this supplement interact with medications?

It is possible L-Methylfolate may interact with certain medications. It is always best to check with a healthcare provider before starting any supplements.

Are there any known side effects?

Most people tolerate it well. If you feel like you are sensitive to higher doses, you can work your way up to the full dose over time.

How do I take it — with food or without?

It can be taken with or without food, but some people prefer it with a meal to avoid mild stomach discomfort.

MEGA B12

I have MTHFR so finding quality methylated b12 and methylfolate is important for maintaining my health. I prefer USDA organic and non GMO supplements. This offers both methylfolate and methylated b12. The liquid is light, fruity, and easy on the palette. It has a mega dose of b12 so I don't take this daily as it can cause anxiety for me. What I like: easy to take, portable, organic, good flavor. A+

L-Methylfolate (1mg) Plus Methyl-B12

I wanted tasteless and clear

Homocysteine coming down

I’ve always had high homocysteine due to MTHFR gene.. thankfully I’ve found a product to help with that! I’m on my third bottle and can tell the difference.. I have leaky gut and my doctor suggested liquid drops for better methylation and it is working! Great product!

LMethtlofolate has been very helpful

I’ve been taking L-Methylfolate (1mg) plus Methyl-B12 for a few weeks now and the difference is amazing. My energy feels steady throughout the day, and my focus has improved more than I expected. I’ve also noticed a big boost in my overall mood and clarity. This combination truly feels like a game-changer for both my mind and body

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Select Your Plan

Key Ingredients

Size / Suggested Use

Product Details

Supplement Facts

Why You’ll Love Our L-Methylfolate

How L-Methylfolate Works in the Body

Body-Ready Nutrients in One Easy Dose

See how L-Methylfolate Helped Others!

* These testimonials represent individual experiences. Participants received free product samples and were compensated for their time, but their opinions are entirely their own and were not influenced by our team. Individual results may vary.

How to Take L-Methyfolate

Which dose is right for you?

3-7 Days: Gradual Support*

Weeks 4-8: Noticeable Support*

Month 3-6: Ongoing Support*

Hear From Our Experts

Quality Standards You Can Trust

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L-Methylfolate (15 mg) Plus Methyl-B12

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