BioActive Vitamin B6 (25mg): P-5-P with Riboflavin & Magnesium Cofactors

Activated B6 with built-in cofactors — the complete system your body needs for mood, energy, and hormonal balance.

  1. Already-active P-5-P form — The exact form your brain uses directly — no conversion needed, works immediately to support neurotransmitters and over 140 enzyme reactions*
  2. B2 & Magnesium cofactors included — B6 alone is only half the formula — riboflavin sustains active B6 levels in the blood while magnesium supports its effects on stress and mood*
  3. 25mg standard strength — Daily maintenance support for energy, hormonal balance, sleep, and cycle comfort in one daily capsule*

60 Capsules · 60 Servings

HSA/FSA Eligible
Pay with
HSA/FSA Eligible
Pay with
Third-Party Tested
Thoughtfully Formulated
Clinically Studied Ingredients
30-Day Satisfaction Guaranteed
Free US Shipping On Orders Over $75

Complete B6 System for Daily Mood, Energy & Hormonal Support
BioActive Vitamin B6 delivers the active form P-5-P—ready for your body to use—paired with key cofactors for more effective support.*

  • Supports Healthy Mood & Stress Response*
  • Promotes Steady Energy & Mental Clarity*
  • Supports Hormonal Balance & Monthly Comfort*

Results may vary. Supports overall wellness alongside a balanced diet and lifestyle.*

  • Steady energy without afternoon crashes
  • Clearer thinking and less brain fog
  • More balanced mood and stress response
  • Healthy sleep pattern support
  • Vitamin B6 (as pyridoxal-5'-phosphate)
  • Vitamin B2 (as riboflavin)
  • Magnesium (as magnesium bisglycinate chelate buffered)

1 capsule daily with food to maximize tolerance & absorption. Take daily for best results.

Pairs with

Is your B6 actually working?

Most B6 supplements use pyridoxine — an inactive form that must be converted by the liver before your body can use it. For many people, that conversion is incomplete, which means most of the B6 they take never actually gets used.*

BioActive B6 delivers Pyridoxal-5-Phosphate (P-5-P), the active form your body recognizes immediately — paired with the cofactors that keep it working all day.*

  • Active, bloodstream-ready P-5-P*
  • No liver conversion required*
  • Paired with riboflavin + Albion® magnesium cofactors*
  • Designed for sustained B6 activity throughout the day*

The System Behind The Results

Each ingredient makes the others work better.

Active B6 — The Performer

Already activated. Powers 140+ enzyme reactions immediately.*

Riboflavin (B2) — The Sustainer

Fuels the recycling enzyme. Keeps B6 active instead of fading.*

Albion® Magnesium — The Optimizer

Works alongside B6 for complementary cellular support.*

 Not All B6 Is Created Equal

Form and cofactors determine how well your B6 functions.

Single B6
P-5-P Only
BioActive B6
Form What you're actually taking
Inactive
Active
Active
Bloodstream ready Whether your body can use it immediately
Riboflavin (B2) Sustains B6 activity throughout the day
5 mg
Albion® Magnesium Works alongside B6 at the cellular level
50 mg
Whole-system approach Form + cofactors together, not in isolation

Clinically Proven Cofactor Synergy

Research backs why we built the formula this way — not B6 alone, but B6 plus the cofactors that keep it working.*

  • 28% Lower active B6 in adults with low riboflavin status — regardless of how much B6 they consume.*

    Jarrett et al., American Journal of Clinical Nutrition, 2022

  • 24% Greater stress reduction with B6 + magnesium vs. magnesium alone, in an 8-week clinical study of adults with severe to extremely severe stress scores.*

    Pouteau et al., PLoS ONE, 2018

What Activated B6 Does For You

B6 powers over 140 enzyme reactions in your body. When it's actually working, you may notice:*

  • Steady energy without afternoon crashes

    B6 helps metabolize carbs, proteins, and fats into usable cellular energy.*

  • Clearer thinking and less brain fog

    Sustained B6 activity supports cognitive function throughout the day.*

  • More balanced mood and stress response

    P-5-P is critical for serotonin, dopamine, and GABA production.*

  • Healthy sleep pattern support

    B6 supports the tryptophan → serotonin → melatonin pathway.*

  • Hormonal balance support for women

    B6 plays a role in estrogen and progesterone metabolism.*

Form Determines How Much Your Body Actually Gets

Most B6 Struggles to Make it to Your Bloodstream

Your body must convert pyridoxine INTO P-5-P. We just give you P-5-P.

Better Sleep Starts With B6

Your body uses B6 to produce melatonin — the hormone that regulates your sleep-wake cycle.


Bó plays a key role in the conversion of tryptophan into serotonin — the precursor to melatonin. When your body has what it needs to run this pathway, restful nights follow.*

Standards Without Compromise

This formula is crafted with thoughtfully selected ingredients and manufactured to rigorous quality standards.

Dairy
Free

Soy
Free

GMO
Free

Gluten
Free

Thoughtfully formulated. Independently tested.

We prioritize transparent sourcing, thoughtful formulation, and third-party testing standards to help ensure quality, purity, and consistency across our products.

Third-Party Tested

Third-Party Tested

Products are independently tested to verify quality, purity, potency, and ingredient standards.

Thoughtfully Sourced Ingredients

Thoughtfully Sourced Ingredients

We partner with trusted suppliers to select premium ingredients backed by research and rigorous quality standards.

Intentional Formulations

Intentional Formulations

Every formula is designed for ingredient compatibility, bioavailability, and effective dosing.

GMP-Certified Manufacturing

GMP-Certified Manufacturing

Manufactured in GMP-certified facilities that follow established quality control standards.

Third-Party Tested
GMP-Certified Facility
Transparent Sourcing
Practitioner-Informed
Quality-Focused

Frequently asked questions

BioActive Vitamin B6 uses the active form your body actually uses — P-5-P — combined with riboflavin and Albion® magnesium to support absorption and sustained activity throughout the day.Most B6 supplements use pyridoxine, an inactive form that must be converted before your body can use it. Even many P-5-P products miss the cofactors needed to keep B6 active.BioActive B6 is built asThe Complete B6 System— designed to deliver B6 that works immediately and stays active, rather than peaking and fading.*

When your B6 is in the active form and supported properly, you may notice more consistent energy, clearer thinking, and a more balanced mood.B6 plays a role in over 140 enzyme reactions that support energy metabolism, cognitive function, and nervous system health.With sustained activity throughout the day, many people experience fewer afternoon crashes, better focus, and for women, improved monthly comfort and cycle-related mood support.*

Both formulas use the same Complete B6 System — the difference is how much support you want.

  • 25mg Standard Strength: Ideal for daily maintenance, general wellness, and long-term use
  • 100mg Maximum Strength: Higher potency for more targeted support, including mood, stress, and women’s cycle wellness

Clinical studies on B6 for cycle support often use doses in the 50–100mg range, which is why some people choose the higher strength.*

Take one capsule daily with food, ideally in the morning.B6 supports neurotransmitters that influence energy and mood, so morning use helps provide steady support throughout the day.Because BioActive B6 is designed for sustained activity, you don’t need to carefully time doses — consistency matters most.*

Results develop over time with consistent use. Some people notice differences within the first few weeks, while the full benefits of sustained B6 support become more apparent with continued daily use.B6 levels build over time, and sustained support becomes more noticeable with continued daily use.For women using it for cycle support, tracking over 2–3 cycles can provide a clearer picture of results.*

BioActive Vitamin B6 uses P-5-P, the form your body actually uses. Because P-5-P is already active, it bypasses the conversion step that limits standard pyridoxine — meaning your body can put it to work right away. As with any supplement, if you are pregnant, nursing, taking medications, or have a medical condition, consult your healthcare provider before use.*As with any supplement, if you are pregnant, nursing, taking medications, or have a medical condition, consult your healthcare provider before use.*

Build Your Complete Routine

Warning: This product contains herbal and nutritional ingredients that may cause mild gastrointestinal discomfort or allergic reactions in sensitive individuals. Consult your healthcare provider before use, especially if you are pregnant, nursing, taking medication, or have a medical condition such as diabetes or liver disease. Discontinue use and consult a healthcare professional if you experience any adverse reactions. Keep out of reach of children. Do not use if seal is broken or missing.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Results may vary. This product should be used in conjunction with a healthy diet and regular exercise

To report a serious adverse event, please contact 844-272-6337.