L-Methylfolate (15 mg) Plus Methyl-B12

Methyl_Folate_Boxt_and_Bottle_with_frontrowMD

do you Prefer Capsules?

Shop Now

L-Methylfolate (15 mg) Plus Methyl-B12

Key Ingredients

Folate
Vitamin B12

Size / Suggested Use

Size: 1 oz - 60 Servings

Product Details

Absorbs directly into the bloodstream and requires no processing from the body.
Contains the essential Cofactor MethylB12.
Supports brain and heart health and contributes to balancing energy, hormones, and mood

L-Methylfolate is the biologically active, bloodstream-ready form of Folate (Vitamin B9). Our formulation provides a maximum strength dose of 15 mg L-Methylfolate. This strength was formulated to support optimal folate levels. The formula also includes a whole serving of Methyl-B12, an essential cofactor to L-Methylfolate. The liquid sublingual form provides enhanced absorption and an enjoyable cherry flavor. It also contributes to the production of neurotransmitters, which are involved in maintaining focus, regulating sleep patterns, providing energy, balancing hormones, and impacting mood. Furthermore, Methylfolate promotes heart health and optimal nerve function.*

Supplement Facts

Quantity

1-Bottle

2-Bottles

3-Bottles

6-Bottles

Purchase Type

Frequency

More payment options

Pay with HSA/FSA Save an average of 30%

Healthy methylation plays a role in many everyday functions:

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Methylated Folate: A Nutrient Form Some People Prefer for Genetic Support*

Certain MTHFR gene variations may affect how the body processes synthetic folic acid. Methylated forms like 5-MTHF can offer a more direct form of folate support.

Methylated vitamins provide folate in a body-ready form, supporting bioavailability and cellular use.*

Up to 40% of people may carry a common MTHFR gene variant.*

Why You’ll Love Our L-Methylfolate

Bloodstream Ready L-Methyfolate*

Designed for Efficient Absorption*

No Conversion Required - Body-Ready Form*

Enhanced with B12*

How L-Methylfolate Works in the Body

Supports neurotransmitters like serotonin, dopamine & norepinephrine.*

Supports red blood cells production and detox in the body.*

Helps your homocysteine levels stay in check which is vital for heart and brain health.*

Body-Ready Nutrients in One Easy Dose

Supports Mood & Cognition*

Supports Healthy Methylation*

Supports Heart Health*

Supports Nerve Cognition*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See how L-Methylfolate Helped Others!

Methylfolate

* These testimonials represent individual experiences. Participants received free product samples and were compensated for their time, but their opinions are entirely their own and were not influenced by our team. Individual results may vary.

How to Take L-Methyfolate

1. Shake well before use.

2. Take 10 droplets directly under tongue

OR mix 10 droplets into your favorite drinks, smoothies or water.

Know your supplement

Our drops are a deep, rich burgundy shade. Please be cautious of counterfeit products that may differ in color or quality. To ensure you receive a genuine product, only purchase from our official websites or stores.

Which dose is right for you?

1 mg Light

Supplementation

Best For: This is a starting dose for general wellness or individuals who want to support methylation.

Learn More

7.5 mg Moderate Supplementation

Best For: Individuals seeking a higher level of methylated folate to support folate metabolism and cellular function.*

Learn More

15 mg High

Supplementation

Best For: Those looking for a higher dose of folate to support advanced nutritional needs or personalized wellness goals, as recommended by a healthcare professional.*

Learn More

Genetic Wellness Support Starts Early

Daily Nutritional Folate support with

KIDS L-Methylfolate

Shop Now

Results Over Time

3-7 Days: Gradual Support*

Some individuals may begin to notice support for mental clarity, mood balance, and energy. This is also when nutritional support for red blood cell formation and homocysteine metabolism may begin.*

Weeks 4-8: Noticeable Support*

Neurotransmitter production for the ‘feel good’ hormones like serotonin & dopamine goes up which can help with an improvement in mood and a reduction in symptoms of anxiety.*

Month 3-6: Ongoing Support*

Some individuals may notice more consistent energy levels and support for healthy eating patterns. Users have also shared feeling more in tune with their overall wellness goals and daily routines.*

Disclaimer: Individual results vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Shop Now

Hear From Our Experts

"As a health researcher, I view L-Methylfolate as an essential nutrient for neurological, emotional, and metabolic balance—especially in individuals with genetic variants like MTHFR. Triquetra’s L-Methylfolate line stands out for its clinically relevant dosing, exceptional purity, and highly bioavailable formulas, with options tailored for both adults and children. It’s a science-backed choice for those seeking therapeutic efficacy and uncompromising quality."

Adriano Zanardi da Silva, M.Sc., Ph.D

Quality Standards You Can Trust

Warning: If you have a medical condition or are taking medication, contact a physician before taking this supplement. Keep out of reach of children.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

To report a serious adverse event, please contact 844-272-6337.

Frequently Asked Questions

What is L-Methylfolate and how is it different from folic acid?

L-Methylfolate is the active form of folate that your body can use immediately. Folic acid needs to be converted—and some people can’t do that well because of genetic mutations like MTHFR.

What is Methyl B12 and why is it paired with L-Methylfolate?

Methyl B12 (aka Methylcobalamin) is a highly bioavailable form of B12 that works synergistically with L-Methylfolate to support brain health, energy, and mood.

Is this product safe if I’m pregnant or breastfeeding?

Check with your doctor first. L-Methylfolate is often recommended during pregnancy, but always confirm with your healthcare provider.

Can this supplement interact with medications?

It is possible L-Methylfolate may interact with certain medications. It is always best to check with a healthcare provider before starting any supplements.

Are there any known side effects?

Most people tolerate it well. If you feel like you are sensitive to higher doses, you can work your way up to the full dose over time.

How do I take it — with food or without?

It can be taken with or without food, but some people prefer it with a meal to avoid mild stomach discomfort.

I swear by this!!

I’ve been using Triquetra Health’s L-Methylfolate 5-MTHF + Methyl B12 every single day for over a year now, and I truly won’t go without it. As someone in long-term recovery, supporting my mental clarity, mood, and energy naturally is a top priority—and this supplement has been a crucial part of that.

It’s rare to find something that’s not only clean and bioavailable, but that actually makes a real difference. I noticed improvements in focus, mood stability, and overall well-being early on, and it’s been consistent ever since. The combination of active folate and methyl B12 is perfect for those of us who can’t process synthetic forms.

If you’re in recovery or just want something that genuinely supports your brain and body, this is one supplement I wholeheartedly recommend. It’s earned a permanent spot in my routine.

Great

Love it

Tastes great!

Works Well

The Liquid Form absorbs quickly.

These drops are wonderful and really do help with energy levels! Just try them!

1 2 3

Key Ingredients

Size / Suggested Use

Product Details

Supplement Facts

Why You’ll Love Our L-Methylfolate

How L-Methylfolate Works in the Body

Body-Ready Nutrients in One Easy Dose

See how L-Methylfolate Helped Others!

* These testimonials represent individual experiences. Participants received free product samples and were compensated for their time, but their opinions are entirely their own and were not influenced by our team. Individual results may vary.

How to Take L-Methyfolate

Which dose is right for you?

3-7 Days: Gradual Support*

Weeks 4-8: Noticeable Support*

Month 3-6: Ongoing Support*

Hear From Our Experts

Quality Standards You Can Trust

Frequently Asked Questions

What is L-Methylfolate and how is it different from folic acid?

What is Methyl B12 and why is it paired with L-Methylfolate?

Is this product safe if I’m pregnant or breastfeeding?

Can this supplement interact with medications?

Are there any known side effects?

How do I take it — with food or without?

Customer Reviews

Explore

Shop

Sign up and never miss brand exclusives and updates!

Sign up and never miss brand exclusives and updates!

Sign up and never miss brand
exclusives and updates!