BioActive Vitamin B1

The complete Vitamin B1 activation system with 5X to 11X higher plasma absorption than standard thiamin

  1. Clinical-Grade Benfotiamine (Vitamin B1) + Precision Cofactors — four active ingredients — highly bioavailable, lipid-soluble benfotiamine paired with chelated magnesium bisglycinate, active P-5-P, and Alpha-Lipoic Acid to deliver complete TPP pathway support directly to your nerve tissues.*
  2. Cofactor-complete activation, not just isolated Vitamin B1 — supplies the critical magnesium (Mg²⁺) required by your body's enzymes to actually convert absorbed Vitamin B1 (thiamine) into its functional, active form — a crucial biological step most benfotiamine supplements leave out.*
  3. Formulated to support nerve comfort, healthy sensation, and cellular energy — a specialized Vitamin B1 formula designed to proactively support healthy sensory function and nerve cell energy metabolism as part of normal aging.*
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Standard thiamine supplements stop at absorption. B1 only becomes functional once your body converts it into its active coenzyme form — a conversion that requires magnesium. BioActive Vitamin B1™ pairs fat-soluble benfotiamine with magnesium, P-5-P, and alpha-lipoic acid to unlock B1's full role in nerve, brain, and cellular energy function.*

Available in two strengths: Foundation Strength (150mg) is our research-informed daily dose for a consistent B1 routine. Maximum Strength (600mg) delivers comprehensive daily support for those with higher B1 needs.*

  • Superior delivery. Benfotiamine has been studied to produce 5–11× higher blood thiamine levels than standard thiamine, reaching the nerve tissue and mitochondria where B1 does its work.*
  • Gentle for daily use. Fat-soluble and absorbed through a natural transport pathway — no flush, no stomach upset, no cycling. Stimulant-free.
  • Clean label. Vegan, gluten-free, non-GMO, soy-free. Manufactured in a GMP-certified facility and third-party tested.

 

  • Nerve Comfort & Function*
  • Cellular Energy Production*
  • Mental Clarity & Focus*
  • Healthy Glucose Metabolism*
  • Antioxidant & Cellular Defense*
  • Heart & Cardiovascular Function*
  • Neurological Health*
  • Thiamine (as Benfotiamine)
  • (Vitamin B1) Magnesium (as Magnesium bisgycinate chelate)
  • Vitamin B6 (as Pyridoxal-5'-phosphate)
  • Alpha-lipoic acid

Take 1 capsule daily with food, preferably with food at breakfast or lunch.

The Optimal Form of B1 with Cofactors to Make it Work

Complete Cofactor System

Enhanced Absorption

Optimized for Daily Support

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

That's the Benfotiamine Difference

5-11× More Usable B1

Form determines how much reaches your cell. Your cells are surrounded by a fat based membrane. Fat-soluble benfotiamine passes through. Water soluble thiamine cannot.

(Xie et al., 2014 — Clinical Pharmacology)

Four Components, One System

Each ingredient is chosen to play a specific role.

Benfotiamine (B1) (150mg)

The bioactive form — delivers 5–11× more B1 to your cells than standard thiamine.*

Magnesium Bisglycinate (18mg)

Required to convert B1 into its active, usable form.*

Alpha-Lipoic Acid (100mg)

Documented synergy with benfotiamine for cellular defense.*

P-5-P (B6) (15mg)

Powers your bWorks alongside B1 through
complementary nerve and energy pathways.*ody's natural calm system*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Every Cofactor Earns Its Place

Each ingredient is chosen to help benfotiamine work better.

  • The Activator

    Your body requires magnesium to convert benfotiamine into active TPP - the form your cells actually use. Without it, B1 is absorbed but never fully activated.*

  • The Nerve Partner

    B1 and B6 work through complementary neurological pathways. Research shows the combination produces greater nerve outcomes than either alone.*

  • The Protector

    Benfotiamine and ALA together deliver more complete cellular protection than either one by itself - documented in published research.*

9+ peer-reviewed studies. One complete system.*

Nerve Comfort & Function

Nerve tissue is one of the most B1-dependent tissues in the body, and one of the hardest to reach with standard thiamine. Benfotiamine was developed specifically to cross into fatty tissue, supporting healthy nerve function where water-soluble B1 falls short.*

Mental Clarity& Focus

Your brain runs on glucose but glucose is useless without B1 to unlock it. Support the enzyme systems that convert sugar into brain fuel, so mental clarity holds steady through the afternoon slump.*

Healthy Glucose Metabolism

Every carbohydrate you eat has to be processed, and B1 is a required cofactor in that process. Benfotiamine supports the enzymes that keep glucose metabolism running smoothly — helping your body do what it's designed to do.*

Antioxidant & Cellular Defense

Stress, pollution, and normal metabolism all generate free radicals that add up over time. Alpha-lipoic acid and activated B1 work together to support your body's natural antioxidant defenses, the ones protecting you from the inside out.*

Cellular Energy & Cardiovascular Support

Energy isn't a caffeine spike. It's what happens when your mitochondria convert food into ATP, the fuel your body actually runs on. Activated B1 supports those reactions in every tissue that never stops working, from your muscles to the heart that beats every second of every day.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Meet Our
Science Advisory Board

Our Science Advisory Board brings research, performance science, and nutritional biochemistry expertise to every formula - grounded in published research.

Dr. Will Aguila, MD

“Your best self isn’t something you create— it’s something you uncover when the body is finally given what it truly needs.”

Dr. Nicole Avena, PhD

“Transparency in formulation empowers people to care for their health with confidence.”

Dr. Dan Sullivan, ND

"Remove what's in the way. Provide what's missing. Trust the process."

Built for People Who Read the Label

  • Every Batch Is Third Party Tested

    Every bottle is independently verified and tested for contaminants and heavy metals before it ever reaches you.

  • Quality Standards You Can Trust

    Our formula is vegan, GMO-free, gluten-free, binders-free, uses low FODMAP ingredients and is manufactured in a GMP certified facility.

  • Clinically Studied Ingredients

    We choose every ingredient based on absorption, potency, and published research.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

BioActive Vitamin B1 Over Time

Results build with consistency. Here's what to expect along the way.

1-4 Weeks

Adjustment Phase

Magnesium turns benfotiamine into the form your cells can actually use — the version that helps your body make energy from food.*

4 - 8 weeks

Work in Progress

Because benfotiamine is fat-soluble, it builds up in tissue that standard water-soluble B1 just passes through.*

8+ Weeks

Feeling the Difference

Three months in is when most people notice the payoff with steadier energy, clearer thinking, better daily function.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Choose the B1 That is Right For You

BioActive B1 - Foundation Strength

  • Key Differentiator: Research-informed daily dose

  • Size/Count: 60 capsules

  • Best For: Everyday nerve and cellular energy support, general wellness, those new to benfotiamine

BioActive B1 - Clinical Strength

  • Key Differentiator: Clinical Trial Dose Formula

  • Size/Count: 60 capsules

  • Best For: Those with higher nerve support needs, comprehensive metabolic support, evidence-driven optimizers

Frequently asked questions

Most benfotiamine products deliver one ingredient. BioActive B1 is a complete system: fat-soluble benfotiamine plus the cofactors that help unlock it — magnesium, active B6 (P-5-P), and alpha-lipoic acid. Absorption is only step one; your body uses magnesium to convert B1 into the coenzyme form your cells actually use.*

Choose Foundation Strength (150mg) for everyday support, once-daily convenience, or if you're new to benfotiamine. Choose Maximum Strength (600mg) if you have higher B1 needs, are following a practitioner-guided protocol, or want stronger daily support. Both use the same complete formula — only the benfotiamine dose differs.*

Standard thiamine is water-soluble and largely flushed before reaching the tissues that depend on it. Benfotiamine is fat-soluble, crossing cell membranes efficiently — studied to produce 5–11× higher blood thiamine levels than standard thiamine.*

Each has a role. Magnesium supports the conversion of B1 into its active coenzyme form. Active B6 (P-5-P) is the ready-to-use form of B6 and works alongside B1 for nerve support. Alpha-lipoic acid is a versatile antioxidant with research-documented synergy alongside benfotiamine.*

Foundation Strength: 1 capsule daily. Maximum Strength: 2 capsules daily. Take with or without food, at a consistent time. BioActive B1 is built for daily cellular support, not a same-day stimulant effect — most people find that consistency over 60–90 days produces the best results.*

No. Because benfotiamine is fat-soluble and absorbed through a natural transport pathway, it's well-tolerated for long-term daily use — no flush, no stomach upset, no cycling required. It's also stimulant-free.

Yes. Every batch is third-party tested for purity and potency and manufactured in a GMP-certified facility. The capsules are vegan, gluten-free, non-GMO, and soy-free — full label transparency, no proprietary blends.

BioActive B1 is generally compatible with comprehensive wellness routines. If you're pregnant, nursing, taking medications, or managing a health condition, check with your healthcare provider before starting any new supplement.

Standards without compromise

We prioritize ingredient purity, thoughtful formulation, and rigorous sourcing standards to support quality and consistency in every batch.

Vegan

GMO
free

Gluten
free

Soy
free

GMP
certified

Third-party
tested

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Laura G.

BioActive Vitamin B1

P
Patricia
Good Vitamin

Im not sure if its working yet. Easy to swallow. I take at night with my other meds. No side affects.

C
Cristina M.

Helping heal neuropathy

Build Your Complete Routine

Warning: If you have a medical condition or are taking medication, contact a physician before taking this supplement. Keep out of reach of children. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

To report a serious adverse event, please contact 844-272-6337.