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Triquetra GLP-Activate natural GLP-1 support supplement bottle and box for appetite control, metabolic support, and weight management
GLP-Activate supplement supporting natural GLP-1 pathways for healthy appetite control, metabolic function, and weight management with daily use
GLP-Activate supplement supporting healthy appetite balance, fullness signals, and metabolic wellness for natural GLP-1 pathway support
Diagram explaining the role of GLP-1 hormone in supporting natural metabolism, appetite regulation, and healthy eating habits with GLP-Activate metabolic support
GLP-Activate supplement directions showing how to take capsules before meals and timeline of appetite balance, energy support, and metabolic wellness results
GLP-Activate scientifically backed ingredients including phenylcapsaicin, berberine, green tea EGCG, Ceylon cinnamon, taurine, curcumin, and boron for metabolic and appetite support
Infographic explaining biological factors affecting GLP-1 levels including genetics, metabolic disorders, age, and diet influencing appetite and weight management
Timeline infographic showing expected benefits of GLP-1 metabolic support including improved energy within days, better metabolism within weeks, and long-term metabolic balance within months
Supplement facts panel for GLP-Activate showing serving size, ingredients including berberine, green tea extract, cinnamon, curcumin, taurine, phenylcapsaicin and boron, with suggested use and quality certifications
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Key Ingredients

  • -Berberine HCI (from Berberis aristata root extract) (40:1 ratio)
  • -Green Tea Extract (from Camellia sinensis leaf) (Standardized to contain 50% EGCG (Epigallocatechin gallate))
  • -Organic Ceylon Cinnamon (from Cinnamomum verum bark)
  • -Aloe Vera (Aloe barbadensis inner leaf gel) (200:1 extract)
  • -Curcumin C3 Complex (from Turmeric Extract (Curcuma longa rhizomes) standardized to contain 95% Curcuminoids)
  • -Taurine
  • -AXIVITE® Phenylcapsaicin (contains natural capsaicin analog)
  • -Boron (as Boron Glycinate)

Size / Suggested Use

  • Size: 90 Capsules - 90 Servings

Product Details

Holistic GLP-1 Support with Each Meal
Many underlying factors contribute to healthy weight management, appetite and eating habits. GLP-Activate was formulated to act as a mealtime companion and provide holistic GLP-1 and metabolic support with each meal.*
  • - Supports Healthy Appetite Control*
  • - Helps Manage Cravings*
  • - Supports Healthy Metabolic Function*
Results may vary. Supports healthy weight management alongside a healthy diet and exercise.* GLP-Activate does not contain synthetic GLP-1 and is not a substitute for GLP-1 agonist drugs.


Supplement Facts

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Real Stories of Healthy Weight Management
GLP-Activate Users Share Their Progress
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Katie, 40 Lost 45 pounds 
in 4 months
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Greg, 37 Lost 30 pounds
in 17 months
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Tonya, 54 Lost 44 pounds
in 11 months
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Jessica, 36 Lost 20 pounds 
in 5 months
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Results may vary. A healthy diet and regular exercise are essential for achieving and maintaining weight management goals. 
Consult your physician before starting any supplement regimen.
*These statements have not been evaluated by the Food and Drug Administration. 
This product is not intended to diagnose, treat, cure, or prevent any disease. Results may vary.
GLP-1 is a key hormone that naturally supports healthy metabolism and appetite.
Individual GLP-1 levels may vary, which can influence normal metabolic processes.*
Why is GLP-1 Important for Metabolism & Appetite?
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*These statements have not been evaluated by the Food and Drug Administration. 
This product is not intended to diagnose, treat, cure, or prevent any disease. Results may vary.
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Great so far!
"Surprisingly, I have lost about 5 lbs in less than 30 days. "
Dr B.A.
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Retail_conference_S10_stars_review
"GLP-Activate, the 1st supplement supporting GLP-1 to optimize appetite & fat burning efficiency."
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Retail_conference_S10_stars_review
It works, y’all
"I’ve never felt so free from hunger and cravings."
-Emily T. 
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Retail_conference_S10_stars_review
"GLP-Activate - Sustainable weight loss help has arrived."
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Retail_conference_S10_stars_review
A Huge Help!
"2 months in, I have lost 20lbs, and am still losing."
-Patterson
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Worth it
"This product is worth all the hype."
-Erica
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This is it!
"Secret Sauce to weight loss"
-Devon W.
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How to Take GLP-Activate

Take 1 capsule, 3 times per day, about 30-60 minutes before meals*

GLP-Activate is formulated with seven research-backed ingredients to support healthy metabolic function and weight management as part of a balanced lifestyle.* Use consistently alongside a healthy diet and regular exercise for best results.
*These statements have not been evaluated by the Food and Drug Administration. 
This product is not intended to diagnose, treat, cure, or prevent any disease. Results may vary.
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Capsule color may vary*
GLP-Activate™ – Daily Mealtime Support for 
Healthy Metabolic Function*
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Supports Healthy Weight Management*
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Helps Manage Cravings*
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Supports Healthy Metabolism*
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Supports Appetite Balance* 
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These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Learn How GLP-Activate is Helping Others
Although individual experiences vary, here is a general timeline that some users report:*
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Week 1: Getting started

Begin taking GLP-Activate about 30 minutes before meals. As with any supplement, your body may take time to adjust — some people notice mild digestive changes early on. Stay consistent and well-hydrated.
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Weeks 2-4: Building a routine

Continued daily use supports a balanced approach to mealtime and steady energy as part of a healthy lifestyle.*
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Month 2: Ongoing support

With consistent use, GLP-Activate may continue to support healthy metabolic function and steady daily energy as part of a balanced routine.*
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Months 3-6: Maintaining momentum

Continued daily use supports healthy weight management as part of a balanced lifestyle that includes diet and regular exercise.*
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Beyond 6 Months: Ongoing balance

With consistent daily use, GLP-Activate may continue to support healthy metabolic function and balanced energy as part of an everyday routine.*
For best results, use alongside a healthy diet and regular exercise.
Individual results may vary. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Trusted by over 1000 Health Experts
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★★★★★
Dr. Adriano Zanardi Da Silva
M.Sc., Ph.D.
GLP Activate is an innovative formulation that supports the body’s natural GLP-1 pathways with clinically studied ingredients such as Berberine, Ceylon Cinnamon, and EGCG. By combining nutrients that help maintain healthy metabolic function, promote thermogenic activity, and support a normal inflammatory response, GLP Activate delivers a well-rounded, research-based approach to healthy metabolism, blood sugar balance already within the normal range, and balanced appetite. Its design offers a natural complement to modern lifestyles, especially for those seeking ongoing, holistic metabolic support.*
★★★★★
Dr. Phil Cowley
Registered Pharmacist
GLP Activate supports your body’s natural GLP-1 pathways by focusing on the cells along your GI lining that produce these hormones. In doing so, it may help with occasional cravings and support healthy weight management, helping you feel more comfortable day to day.*
★★★★★
Ben Tzeel
T1D Diabetes Dietitian
I’m a fan of GLP-Activate for anyone looking to support normal blood sugar levels already within a healthy range. It may help maintain healthy glucose metabolism after meals and assist with occasional cravings, which can encourage a balanced nutrition plan over the long term—key for supporting healthy weight management. Triquetra is committed to using only high-quality ingredients, and by using premium berberine and green tea extract, GLP-Activate stands out as a top choice for comprehensive, holistic metabolic support.*
*Results may vary based on individual. No results guaranteed. Testimonials represent generalized interpretation of real experiences.
What’s Inside
Axivite™ Phenylcapsaicin
A cutting-edge form of Capsaicin. Phenylcapsaicin has been studied for its potential role in supporting normal metabolic function and comfortable digestion.*
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Curcumin C3® Complex 
Derived from turmeric, Curcumin supports healthy digestion and may help maintain balanced metabolic function.*
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EGCG from Green Tea Extract
EGCG from Green Tea Extract can help support normal metabolic processes and overall well-being.*
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Boron
Boron is an essential mineral that may help maintain healthy energy metabolism and overall wellness.*
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Ceylon Cinnamon Extract
Ceylon Cinnamon Extract is often associated with helping support healthy digestion and balanced metabolism.*
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Taurine
Taurine is an essential amino acid that plays a supportive role in overall wellness and normal metabolism.*
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Berberine HCI
A botanical extract from the Berberis Arista plant, Berberine HCl has been studied for its role in helping maintain normal metabolic function and balanced health.*
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Customer Reviews

Based on 202 reviews
71%
(144)
12%
(25)
6%
(13)
4%
(9)
5%
(11)
C
Cyri P.T.
I'm glad I didn't listen to the bad reviews on here...

Cross-posting my review from Amazon, though I purchased this directly thru the Triquetra site.

I have only been taking this for 3 days now, and just 1-2 caps a day instead of the recommended 3 (I dont usually eat breakfast since I can't tolerate food in the early AMs,) and have already seen a change visually in my stomach with the bloating.

What people need to realize more is that any sort of supplement is going to take time to 1.) build up in your body in effectiveness, and 2.) that everyone metabolizes supplements differently. Don't give up hope just because you are not seeing a change in numbers on the scale!! :) Remember: Muscle weighs more than fat, so while you may not be seeing the numbers go down, that doesn't necessarily mean things aren't changing for you on the inside! It is better do do physical measurements and take daily photos of your progress (even if you feel like there is none,) because once you have enough of that data build up, you may better realize the actual change.

1 star taken off because this will definitely make you have some bowel turmoil at first, be prepared for an excess of stool as it does it's job, haha.

T
The E.
Glp trio

I’ve been using the GLP Trio for a little while now, and I wanted to share my honest thoughts for anyone who’s curious or considering trying it. I started it mainly for weight management and to support my metabolism—and I’ve definitely noticed some changes.

✅ Appetite Control: One of the first things I noticed was how much it helped curb my appetite. I wasn’t constantly snacking or reaching for food out of boredom, which made sticking to my eating goals a lot easier.

⚖️ Weight Changes: I did start to lose weight, but it felt natural—not rapid or extreme. The scale moved down steadily, and more importantly, I felt less bloated and more in control of my eating habits.

💊 How I Feel: Energy-wise, I didn’t get jittery or feel off. I actually felt more balanced throughout the day, and it didn’t mess with my mood or digestion, which I was a little worried about at first.

🌿 My Routine: I’ve been pairing it with better meal choices, drinking water, and staying active. I don’t believe in magic pills, but this felt like it gave me a helpful push in the right direction.

So far, I’d say it’s worth trying if you’re looking for a gentle way to support your weight goals—especially if appetite control is a struggle for you. As always, I recommend checking in with your doctor if you have any health concerns, but for me personally, it’s been a positive experience.

V
Victoria
Works Just as it Claims!

I started taking GLP-Activate about two months ago. With a healthy diet & consistent workout, it works great! I had stubborn belly weight I couldn’t lose after kids, hormones, life and stress made it hard to lose. I lost 12 lbs since I started. I posted a photo of my scale app to show my weight loss .

My appetite and cravings have gone down, I have more control over what I eat, feel fuller longer and my bloating has decreased immensely! Consistency is key. Nothing is a miracle drug, but you have to put in work also.

C
Cheryl
Stops Food Noise

So far what I have noticed while taking the product is that it helps to stop the “food noise” / constantly thinking about food &/or my next meal. With that noise gone I am not snacking as much. I was previously on semiglutide & in comparison the “food noise” being greatly reduced is pretty similar. I have not lost any weight, but also have only been using the product for about a week now.

J
Jean B.
Amazing!

I finished my very first bottle of the GLP Activate and have ordered a second! I lost 20lbs in the 30 days that the bottle lasted! I took the supplement as directed on bottle 3 x’s a day, 30-45 mins before a meal. I didn’t experience any issues at all. No cravings whatsoever. I did adopt a plant based diet because I was inspired to eat healthy! I have more energy and am grateful that I saw this product @philsmypharmacist on Instagram. Very pleased! I’m hoping for continued weight loss with the help of this supplement. I have not exercised at all! I want to change that, but considering the fact that I didn’t and still lost weight is remarkable. I’m 52 and pre-menopausal, which has its own challenges! I’m very happy so far!

Frequently Asked 
Questions

*These statements have not been evaluated by the Food and Drug Administration. 
This product is not intended to diagnose, treat, cure, or prevent any disease. Results may vary.

What is GLP-Activate?

GLP-Activate is a dietary supplement formulated with seven research-backed ingredients — Berberine HCl, EGCG from Green Tea Extract, Ceylon Cinnamon, Aloe Vera, Curcumin C3 Complex®, Taurine, AXIVITE® Phenylcapsaicin, and Boron — designed to support healthy metabolic function as part of a balanced lifestyle.*

How does GLP-Activate fit into a daily routine?

Take GLP-Activate before meals as part of a daily wellness routine. Use consistently alongside a healthy diet and regular exercise for best results.*

How should I take GLP-Activate?

Take 1 capsule, up to 3 times daily, about 30 minutes before meals.

What are the key ingredients?

Each capsule contains Berberine HCl, EGCG from Green Tea Extract, Organic Ceylon Cinnamon, Aloe Vera, Curcumin C3 Complex®, Taurine, AXIVITE® Phenylcapsaicin, and Boron. See the Supplement Facts panel for the full ingredient amounts.

Can GLP-Activate support healthy weight management?

GLP-Activate is formulated to support healthy weight management as part of a balanced lifestyle that includes a healthy diet and regular exercise.* Individual results vary.

Who should talk to a doctor before taking GLP-Activate?

Consult your healthcare provider before use — especially if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use and consult a healthcare professional if you experience any adverse reactions. Keep out of reach of children.
Got A Question? Ask Now
Warning: This product contains herbal and nutritional ingredients that may cause mild gastrointestinal discomfort or allergic reactions in sensitive individuals. Consult your healthcare provider before use, especially if you are pregnant, nursing, taking medication, or have a medical condition such as diabetes or liver disease. Discontinue use and consult a healthcare professional if you experience any adverse reactions. Keep out of reach of children. Do not use if seal is broken or missing.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Results may vary. This product should be used in conjunction with a healthy diet and regular exercise

To report a serious adverse event, please contact 844-272-6337.