BioActive B12: Vitamin B12 Plus L-Methylfolate

Full-spectrum liquid B12 to support energy, metabolism, and methylation.*

  1. Three bioactive forms in one liquid formula — Methylcobalamin, adenosylcobalamin, and hydroxocobalamin, which work along different biological pathways in the body
  2. Maximum-strength formula with L-Methylfolate — Delivers 5,000 mcg of vitamin B12 plus 1,000 mcg of L-Methylfolate, an essential B12 cofactor that supports healthy methylation*
  3. Supports healthy B12 status — Designed to support mitochondrial energy production, metabolism, brain and nerve health, mood, and detoxification*

60 capsules · 60 servings

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  • BioActive delivers 3 most beneficial forms of Vitamin B12: Methylcobalamin, Adenosylcobalamin, and Hydroxocobalamin.
  • Contains a full serving of L-Methylfolate, an essential cofactor of B12.
  • Designed to raise overall B12 status levels and support mitochondrial energy production, metabolism, and detoxification.

BioActive B12 is full-spectrum vitamin B12. The formulation contains the 3 essential bioactive forms of B12; Methylcobalamin, Adenosylcobalamin & Hydroxocobalamin. Each form of B12 works along different biological pathways within the body. The formula also provides a whole serving of L- Methylfolate (vitamin B9), an essential cofactor of B12.

  • Supports energy & metabolism*
  • Supports brain & nerve health*
  • Supports mood & cognitive function*
  • Supports healthy methylation*
  • Methylcobalamin
  • Adenosylcobalamin
  • Hydroxocobalamin
  • L-Methylfolate

Take 1 capsule per day, ideally on an empty stomach.

Optimize Your B12 Levels

BioActive B12supports:

Energy & Metabolism*

Brain & Nerve Health*

Mood & Cognitive Function*

Methylation Health*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The 3 Bioactive Forms of B12

Methyl-B12
The Essential Form

The most important form for carrying out essential functions of B12 in the body.

Adenosyl-B12
The Cellular Form

Aids the mitochondria of the cells to burn food more efficiently for energy production & metabolism.

Hydroxy-B12
The Storage Form

The most important form for carrying out essential functions of B12 in the body.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Enhanced Absorption with L-Methylfolate Cofactor

L-Methylfolate (vitamin B9) is a crucial co-factor to vitamin B12 because both play a vital role in the body’s methylation process. Without adequate methylfolate levels, the body may not properly utilize vitamin B12.

Maximum Strength Dose

  • Maximum strength dose

    5,000 mcg of vitamin B12
  • L-Methylfolate cofactor included

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Standards Without Compromise

This formula is crafted with thoughtfully selected ingredients and manufactured to rigorous quality standards.

GMO
Free

Gluten
Free

Vegan

Soy
Free

Thoughtfully formulated. Independently tested.

We prioritize transparent sourcing, thoughtful formulation, and third-party testing standards to help ensure quality, purity, and consistency across our products.

Third-Party Tested

Third-Party Tested

Products are independently tested to verify quality, purity, potency, and ingredient standards.

Thoughtfully Sourced Ingredients

Thoughtfully Sourced Ingredients

We partner with trusted suppliers to select premium ingredients backed by research and rigorous quality standards.

Intentional Formulations

Intentional Formulations

Every formula is designed for ingredient compatibility, bioavailability, and effective dosing.

GMP-Certified Manufacturing

GMP-Certified Manufacturing

Manufactured in GMP-certified facilities that follow established quality control standards.

Third-Party Tested
GMP-Certified Facility
Transparent Sourcing
Practitioner-Informed
Quality-Focused
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  • 5 stars: 235 (89%)
  • 4 stars: 22 (8%)
  • 3 stars: 3 (1%)
  • 2 stars: 0 (0%)
  • 1 star: 3 (1%)
S
Sara D.
B12 Supplement. Three Bioactive Forms of B12.

I have to confess that I was not aware of the various forms of B12. The company claims that the three forms enhance the bioactivity aspects of the B12. Per capsule, it includes a considerable quantity of Vitamin B12, 5000mcg, which is 208,333%DV. Wow. In addition, they add 1667mcg DFE of Vitamin B9 (primarily from L-5 Methylfolate), 417%DV. The Vitamin B9 serves as a cofactor to enhance facilitation of cellular utilization of Vitamin B12.The product details has a picture that notes a number of badges: Vegan, Made In USA, Gluten-Free, GMO-Free and GMP Certified. The GMP Certified (Good Manufacturing Practice) is absent from the actual product packaging/labels. cGMP ensures quality control aspects; the lack of this certification (and no other credible certification) negatively impact the rating.Since I’ve been on a mainly vegan diet, my physician recommended that I take a B12 supplement. This product definitely satisfies that concern. I feel this B12 supplement rates 4.25 stars.

S
Sname O.

Bio active methyl folate

I
Isabel N.
Very Effective!

B-12 vitamins are a big part of my routine and keeping up my energy. A good brand can be very hard to find though! This one has been great because I can take it in the morning without getting an upset stomach. I feel it working faster than other store-bought brands and the natural energy helps my mental clarity throughout the day!

E
Ernesto B.
Easy to swallow and no aftertaste

I take these with folic acid - they are easily to swallow, have no aftertaste, and I like the ingredient list.

N
Natwar K.
Easy to swallow and no aftertaste

I take these with folic acid - they are easily to swallow, have no aftertaste, and I like the ingredient list.

R
Rajesh P.
B12 Supplement. Three Bioactive Forms of B12.

I have to confess that I was not aware of the various forms of B12. The company claims that the three forms enhance the bioactivity aspects of the B12. Per capsule, it includes a considerable quantity of Vitamin B12, 5000mcg, which is 208,333%DV. Wow. In addition, they add 1667mcg DFE of Vitamin B9 (primarily from L-5 Methylfolate), 417%DV. The Vitamin B9 serves as a cofactor to enhance facilitation of cellular utilization of Vitamin B12.The product details has a picture that notes a number of badges: Vegan, Made In USA, Gluten-Free, GMO-Free and GMP Certified. The GMP Certified (Good Manufacturing Practice) is absent from the actual product packaging/labels. cGMP ensures quality control aspects; the lack of this certification (and no other credible certification) negatively impact the rating.Since I’ve been on a mainly vegan diet, my physician recommended that I take a B12 supplement. This product definitely satisfies that concern. I feel this B12 supplement rates 4.25 stars.

S
Siphokazi B.

Really gave me more energy and a sense of well being

N
Nompumelelo M.
Book Active B12 really works!

Since I started taking these, I feel energetic! The capsules area very easy to swallow. Also, it does not upset your stomach!

H
Haylee J.
Book Active B12 really works!

Since I started taking these, I feel energetic! The capsules area very easy to swallow. Also, it does not upset your stomach!

M
Mandla M.
Very Complete Form of Vitamin B-12

This is a very complete form of B-12. Usually vitamin B-12 supplements only provide the methylcobalamine form of B-12, which is the essential form your body needs. This product also supplies the adenosylcobalamin, which helps the cellular mitochondria transport the B-12 around the body and convert food into energy. It also provides hydroxocobalamin which helps the B-12 stay longer in the bloodstream longer and helps in detoxification throughout the body.Vitamin B-12 is needed throughout the body to help form red blood cells and DNA. It is also key in the development of the nerve and brain cell function, as well as mood, energy, and metabolism.This bottle provides a two-month supply of B-12. Only one capsule a day is needed to provide 5000 mcg of these three forms of B-12, as well as L-methylfolate which is an essential co-factor of B-12. This product arrived very well packaged and sealed. Each gel capsule is about 7/8" long and is very light and easy to swallow. I absolutely feel comfortable giving this product the full 5 stars and recommending it to others.

C
Camron K.
Baja en grasa

Multivitaminico bajo en grasa muy bueno para mantener la piel bien

J
Jefferey F.
Baja en grasa

Multivitaminico bajo en grasa muy bueno para mantener la piel bien

J
Jefferey F.
Baja en grasa

Multivitaminico bajo en grasa muy bueno para mantener la piel bien

E
Eloy B.
B12

Not really a taste comes in nice packaging decent price no after taste

A
Augustina N.
B12

Not really a taste comes in nice packaging decent price no after taste

A
Akhil K.
Very Effective!

B-12 vitamins are a big part of my routine and keeping up my energy. A good brand can be very hard to find though! This one has been great because I can take it in the morning without getting an upset stomach. I feel it working faster than other store-bought brands and the natural energy helps my mental clarity throughout the day!

Y
Yadira R.
Very Complete Form of Vitamin B-12

This is a very complete form of B-12. Usually vitamin B-12 supplements only provide the methylcobalamine form of B-12, which is the essential form your body needs. This product also supplies the adenosylcobalamin, which helps the cellular mitochondria transport the B-12 around the body and convert food into energy. It also provides hydroxocobalamin which helps the B-12 stay longer in the bloodstream longer and helps in detoxification throughout the body.Vitamin B-12 is needed throughout the body to help form red blood cells and DNA. It is also key in the development of the nerve and brain cell function, as well as mood, energy, and metabolism.This bottle provides a two-month supply of B-12. Only one capsule a day is needed to provide 5000 mcg of these three forms of B-12, as well as L-methylfolate which is an essential co-factor of B-12. This product arrived very well packaged and sealed. Each gel capsule is about 7/8" long and is very light and easy to swallow. I absolutely feel comfortable giving this product the full 5 stars and recommending it to others.

A
Atul M.
Maximum strength B12

Healthline says "B12 (cobalamin). Perhaps the most well-known of all the B vitamins, B12 is vital for neurological function, DNA production, and red blood cell development." It may also help to convert food into energy.These Vitamin B12 capsules are large but still easy to swallow. They contain 5000 mcg (maximum strength) of B12 plus other related versions of B12. The cost is competitive or lower than other commercial Vitamin B12 products.P.S. I have had trouble sleeping after using these. I do not know if the 5000 mcg capsules are the problem, but I have gone back to 500 mcg capsules.

R
Refiloe N.

Really gave me more energy and a sense of well being

Build Your Complete Routine

Warning: If you have a medical condition or are taking medication, contact a physician before taking this supplement. Keep out of reach of children. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

To report a serious adverse event, please contact 844-272-6337.