A supplement bottle with a white cap, standing next to its matching blue and white cardboard box. The label reads "Triquetra BioActive B-Complex Max Strength." Subtext indicates it is an "Active + Methylated B Vitamin Complex" dietary supplement containing 60 capsules. The box also highlights "Cognitive, Metabolic & Energy Support" and lists vitamins B12, B9, B7, B6, B5, B3, B2, and B1.
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
Triquetra BioActive B-Complex

Still not quite feeling like yourself?

BioActive B-Complex delivers active, ready-to-use B vitamins that support normal energy production, nervous system health, and a balanced mood* — in the form your body doesn’t have to convert first.
  • All-day energy, not a jolt. Active B vitamins help your body turn food into steady, usable energy — no stimulants, no c

  • Full-spectrum active B12. Methyl, Adenosyl & Hydroxo B12 — supports normal cellular energy production and nervous system function.*

  • Active, methylated forms. L-Methylfolate (5-MTHF) plus branded BenfoPure® B1 and Pantesin® B5 — forms your body uses without an extra conversion step.*

✓  Methylation-friendly · Active 5-MTHF folate

Select option: 180 Count
DELIVER EVERY:
Secure checkout VISA MC AMEX PayPal Pay
  • Free Shipping

  • 30-day guarantee

  • 3rd-Party Tested

  • Cancel Anytime

Subscribe & Save

Free birthday gifts included

bc-free-gifts
*This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Not a substitute for medical car
Active & Methylated Forms
L-Methylfolate (5-MTHF)
Full-Spectrum Active B12
BenfoPure® B1 · Pantesin® B5
Vegan · Non-GMO
Third-Party Tested
One Capsule a Day
A woman smiling at her home-desk with a glass of water and laptop, looking out the window
You might be here because—

Running low on energy, and looking for real support.

  • Your energy dips by mid-afternoon and you want steady support, not another coffee
  • You’ve tried a multivitamin or B-complex and something still isn’t quite clicking
  • You’ve heard that some people process folate differently and wondered if that applies to you
  • You’ve looked at a supplement label, seen “folic acid,” and wondered if that matters
  • You’re looking for active-form nutritional support — not a diagnosis

That’s exactly who we made this for.

From the community

Real people, real routines.

Creators and customers sharing how BioActive B-Complex fits into their day.

Individual results vary. Creators may be compensated. *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Folic acid vs. folate

“Folic acid” and “folate” are not the same thing. This one uses the active form.

Active, not synthetic

L-Methylfolate (5-MTHF) and methylcobalamin are already in the form your body uses — no extra conversion step required.*

Full-spectrum B12

Methyl, Adenosyl, and Hydroxo B12 together — supporting normal cellular energy and nervous system function.*

Branded, better-absorbed actives

BenfoPure® Benfotiamine (B1) and Pantesin® Pantethine (B5) — superior forms over standard thiamine and pantothenic acid.*

Clean & verified

All 8 B vitamins, plus choline & inositol. Vegan, non-GMO, gluten- and soy-free. Third-party tested, made in a GMP facility.

Folic acid path: synthetic folic acid must be converted by MTHFR before your body can use it, so only a limited amount reaches your body. Active folate path: 5-MTHF (L-Methylfolate) needs no conversion step and is ready for your body to use right away.
What’s inside

Active nutrient forms, formulated for absorption.

What’s insideHow it’s formulatedWhat it supports
Full-spectrum active B12Methyl B12, Adenosyl B12, Hydroxo B12Supports normal cellular energy production and nervous system function.*
L-Methylfolate (5-MTHF)The active form of folateAn active form of folate that supports normal cell metabolism and red blood cell formation.*
BenfoPure® B1 & Pantesin® B5Benfotiamine & PantethineBetter-absorbed forms that support normal energy metabolism.*
B2, B3, B6, B7Riboflavin, Niacin, P-5-P, BiotinRound out all 8 B vitamins that support overall metabolic health.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have a medical condition. Individual results may vary.

What it supports

Active B vitamins that support how your body actually runs.

Normal energy production

B vitamins help your body turn food into usable energy.*

Nervous system health

Support for normal nervous system function.*

Cognitive function

Support for normal cognitive function.*

Red blood cell formation

L-Methylfolate and B12 support normal red blood cell formation.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have a medical condition. Individual results may vary.

The honest timeline

The first signs show in weeks. The steady feeling builds over months.

B vitamins support your body’s everyday processes, so the change is gradual and compounding. Here’s the honest version of what to expect.

Week 1

Start Gentle

One capsule a day, with food — especially if you know you’re sensitive to active-form B vitamins. Nothing to feel yet; you’re just setting the routine.

Weeks 2–4

It Starts Working

Most people notice a difference in here — steadier energy through the day. For some it takes longer, and that’s normal, not a sign it isn’t working.

Ongoing

Your New Normal

Taken at the same time each day, it supports your body’s normal, everyday processes.* With B vitamins, consistency matters more than dose.

As with any new supplement, we recommend starting with one capsule with food — and checking with your healthcare provider first if you’re pregnant, nursing, or taking medication.

How to take it

One capsule daily, with a meal. Morning or night — consistency is what matters.

Individual results vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

4.7 stars · 1,700+ reviews · Amazon’s Choice

The kind of difference people can feel.

6,000+ people started BioActive B-Complex this month.

★★★★★
Formulation & science
I've tried several B-complex supplements over the years, and the thing that always frustrated me was the disconnect between the label and what my body was actually getting… The B12 alone is worth calling out. Most supplements give you cyanocobalamin (a synthetic form). This one uses all three coenzyme forms — Methylcobalamin, Adenosylcobalamin, and Hydroxocobalamin… Within the first week I noticed a modest but real uptick in mental clarity and sustained energy through the afternoon… No jitteriness, no neon-yellow urine overload.
Brian A.Verified Purchase · Amazon · May 4, 2026
★★★★★
Formulation & science
Bioavailable B vitamins are important. It is also important to not get too much vitamin B6, and this supplement wisely has only 10mg in it. This supplement offers clinically relevant amounts of vitamin B9 and B12 in bioavailable forms… I recommend this to all my family and friends because even with a sufficient diet, it is still very common for people to be deficient in at least one B vitamin.
Ryan R.Verified · triquetrahealth.com · 01/29/2026
★★★★★
Formulation & science
It's gentle on my stomach but still gives me noticeable energy and focus without any jitters. I like that it's methylated and bloodstream ready — it seems to absorb so much better than other B complexes I've tried in the past.
Lauren B.Verified Purchase · Amazon · Feb 24, 2026
★★★★★
Everyday energy
Very good. My husband has even started taking it and he won't take anything! Feel the energy difference. Mid afternoon slump gone! In our mid 50s have more energy.
Ronetta ThackerVerified Purchase · Amazon · Aug 10, 2026
★★★★★
Everyday energy
Definitely notice a difference in the first couple of days. I had more energy through the day to get my honey-do list knocked down a bit.
Robert ThackerVerified Purchase · Amazon · Aug 14, 2026
★★★★★
Everyday energy
Haven't tried a Triquetra product I didn't like and this one is no different. Appreciate how easy they are for the body to absorb. Has helped with the brain fog, and my overall energy. So glad I decided to give it a try.
Melanie S.Verified · triquetrahealth.com · 03/30/2026
★★★★★
Ease of use & format
If you have difficulty taking b vitamins because of the smell, taste, or hate taking pills, you will love this B vitamin — it's mild tasting and you can easily mix it into juice or drink it directly. My 16 year old needs b vitamins and I've had the hardest time getting her to take them until I received this product… slightly sweet berry taste. I love that it comes with a measuring cup. It's a higher quality product because of the 3 different forms and ability to get into bloodstream effectively.
Sara M.Verified · triquetrahealth.com · 07/13/2026
★★★★★
Ease of use & format
This vitamin comes in a glass amber bottle. It's expensive but it is worth it. No adverse effects from this — as some others caused dark yellowing of urine and also would repeat on me. This does neither. I will continue to buy it as it keeps me feeling good.
Roe P.Verified Purchase · Amazon · Jul 14, 2026

Reviews are verbatim from verified purchasers and reflect individual experience, not typical results. Individual results vary. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Dr. Will Aguila, MD — Internal Medicine
Dr. Will Aguila, MDInternal Medicine
Dr. Nicole Avena, PhD — Neuroscience & Nutrition
Dr. Nicole Avena, PhDNeuroscience & Nutrition
Dr. Dan Sullivan, ND — Naturopathic Medicine
Dr. Dan Sullivan, NDNaturopathic Medicine
The Science Advisors

Held to a higher standard.

Independent clinicians and scientists review our formulas — not to endorse them, but to challenge them.

  • Independent oversight.Practicing clinicians and researchers review Triquetra formulas against the published evidence — on an ongoing basis, in market, with real-world outcomes informing every cycle.
  • Reviewed against the published evidence.Every dose, every form, every cofactor pairing is checked against the clinical literature. If the science doesn’t support a claim, the claim doesn’t ship.

Advisors are compensated for their time and expertise, never for endorsement.

Straight answersQuestions, answered
As with any supplement — especially if you’re pregnant, nursing, taking medication, or managing a health condition — check with your healthcare provider before starting.
Try BioActive B-Complex

If it’s not right, we’ll make it right.

Subscribe & Save so you never run out — and if BioActive B-Complex isn’t a fit, our 30-day money-back guarantee has you covered.