Triquetra BioActive Vitamin B6 P5P 100mg Maximum Strength — Complete B6 System bottle
Woman taking BioActive B6 supplement capsule as part of daily wellness routine
BioActive Vitamin B6 P-5-P active form diagram showing conversion of B6 into its coenzyme form with supplement bottle
BioActive Vitamin B6 cofactor system diagram showing P-5-P active B6, riboflavin, and magnesium roles with capsules
Vitamin B6 comparison chart showing pyridoxine inactive form versus P-5-P active form and bloodstream absorption differences
Woman holding BioActive Vitamin B6 bottle with infographic listing activated B6 functions including energy, cognition, mood, sleep, and hormones
BioActive Vitamin B6 infographic showing riboflavin and magnesium cofactors with clinical data percentages and supplement bottle
BioActive Vitamin B6 supplement facts panel showing P-5-P 100mg, riboflavin, and magnesium with GMP and third-party tested icons
BioActive Vitamin B6 (100mg): P-5-P with Riboflavin & Magnesium Cofactors
BioActive Vitamin B6 (100mg): P-5-P with Riboflavin & Magnesium Cofactors
Triquetra BioActive Vitamin B6 P5P 100mg Maximum Strength — Complete B6 System bottle
Woman taking BioActive B6 supplement capsule as part of daily wellness routine
BioActive Vitamin B6 P-5-P active form diagram showing conversion of B6 into its coenzyme form with supplement bottle
BioActive Vitamin B6 cofactor system diagram showing P-5-P active B6, riboflavin, and magnesium roles with capsules
Vitamin B6 comparison chart showing pyridoxine inactive form versus P-5-P active form and bloodstream absorption differences
Woman holding BioActive Vitamin B6 bottle with infographic listing activated B6 functions including energy, cognition, mood, sleep, and hormones
BioActive Vitamin B6 infographic showing riboflavin and magnesium cofactors with clinical data percentages and supplement bottle
BioActive Vitamin B6 supplement facts panel showing P-5-P 100mg, riboflavin, and magnesium with GMP and third-party tested icons
BioActive Vitamin B6 (100mg): P-5-P with Riboflavin & Magnesium Cofactors
BioActive Vitamin B6 (100mg): P-5-P with Riboflavin & Magnesium Cofactors
BioActive Vitamin B6 (100mg): P-5-P with Riboflavin & Magnesium Cofactors
The Complete B6 System Your Cells Need

Select Your Plan

Key Ingredients

  • Vitamin B6 (as pyridoxal-5'-phosphate)

  • Vitamin B2 (as riboflavin)

  • Magnesium (as magnesium bisglycinate chelate buffered)

Size / Suggested Use

  • Size:  60 Capsules - 60 Servings

Product Details

Complete B6 System for Daily Mood, Energy & Hormonal Support
BioActive Vitamin B6 delivers the active form P-5-P—ready for your body to use—paired with key cofactors for more effective support.*

  • Supports Healthy Mood & Stress Response*
  • Promotes Steady Energy & Mental Clarity*
  • Supports Hormonal Balance & Monthly Comfort*

Results may vary. Supports overall wellness alongside a balanced diet and lifestyle.*


Supplement Facts

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B2 & Magnesium
Cofactors

Clinically
Studied Dose

High Potency
Dose

Is Your B6 Actually Working?
Form and cofactors determine how well your B6 functions.
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Most B6 Struggles to Make it to Your Bloodstream
Form Determines How Much Your Body Actually Gets
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The System Behind The Results
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Each ingredient makes the others work better.
B6 Alone Is Only Half the Formula
Research shows that adults with low riboflavin have significantly lower active B6 levels in the blood - regardless of how much B6 they consume.*
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28% lower active B6 in adults with low riboflavin status
*Jarrett et al., American Journal of Clinical Nutrition, 2022
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Magnesium: 
The Missing Piece
24% greater reduction in stress scores with B6 + Magnesium vs. magnesium alone.*

  • B6 and magnesium are complementary at the cellular level

  • Involved in B6 enzyme activation

  • Often depleted in modern diets

We use bioavailable magnesium in our formula to leave nothing to chance.
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What Activated B6 Does For You

B6 powers over 140 enzyme reactions in your body. When your B6 is actually working, you may notice:*
Steady Energy without Afternoon Crashes*
Clearer Thinking and Less Brain Fog*
More Balanced Mood and Stress Response*
Healthy Sleep Pattern Support*
Hormonal Balance Support for Women*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
B6 Plays a Special Role in Women's Health
B6 is involved in estrogen and progesterone metabolism — two hormones central to cycle, mood, and energy.*

  • Healthy hormone metabolism

  • Menstrual comfort and cycle-related ease

  • Estrogen and progesterone balance

Riboflavin helps support sustained B6 activity throughout the day for consistent cycle support*
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B6 Supports the Brain Chemicals That Keep You Feeling Balanced
Vitamin B6 is critical for neurotransmitter synthesis.

  • Serotonin (mood, well-being)

  • Dopamine (motivation, focus)

  • GABA (calm, relaxation)

P-5-P is the exact form your brain uses for neurotransmitter production. No conversion delay.*
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Better Sleep Starts 
With B6
Your body uses B6 to produce melatonin — the hormone that regulates your sleep-wake cycle.

B6 plays a key role in the conversion of tryptophan into serotonin — the precursor to melatonin. When your body has what it needs to run this pathway, restful nights follow.*
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B6 is Essential for Converting Food into Cellular Energy
B6 is what helps your body metabolize carbohydrates, proteins, and fats.

When it is working properly, you experience more consistent energy throughout the day — not a spike and crash, but steady fuel.*
* We add Riboflavin to help sustain B6 activity, so energy support stays consistent throughout the day.*
SUBSCRIBE & SAVE

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NEVER RUN OUT

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Simple to Take. Designed to Work.

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Simple to Take. Designed to Work.

Recommended for best results
1 capsule daily with food to maximize tolerance & absorption. Take daily for best results.
Vitamin-B6-S6_badges
NOTE: The 100mg Maximum Strength provides clinical-level B6 support often recommended by 
practitioners for targeted therapeutic use. For daily maintenance, see our 25mg Standard Strength formula.
NOTE: The 100mg Maximum Strength provides clinical-level B6 support often recommended by practitioners for targeted therapeutic use. For daily maintenance, see our 25mg Standard Strength formula.
Choose the B6 That Is Right For You
BioActive B6 – Standard Strength
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  • Key Differentiator: Daily maintenance dose

  • Size/Count: 60 capsules (2-month supply)

  • Best For: Everyday B6 support, general wellness, those new to P-5-P supplementation

BioActive B6 - High Potency
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  • Key Differentiator: Clinical Dose Formula

  • Size/Count: 60 capsules (2-month supply)

  • Best For: Those with higher B6 needs, practitioner-guided supplement, comprehensive support goals.

Formulated with Doctors. Backed by Research.
Our Science Advisory Board brings medical, neuroscience, and functional medicine expertise to every formulation decision - grounded in published research.
Vitamin-B6_Header_S6_doctors
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Frequently Asked Questions

What makes BioActive Vitamin B6 different from other B6 supplements?

BioActive Vitamin B6 uses the active form your body actually uses — P-5-P — combined with riboflavin and Albion® magnesium to support absorption and sustained activity throughout the day.

Most B6 supplements use pyridoxine, an inactive form that must be converted before your body can use it. Even many P-5-P products miss the cofactors needed to keep B6 active.

BioActive B6 is built as The Complete B6 System — designed to deliver B6 that works immediately and stays active, rather than peaking and fading.*

What benefits can I expect from taking BioActive Vitamin B6?

When your B6 is in the active form and supported properly, you may notice more consistent energy, clearer thinking, and a more balanced mood.

B6 plays a role in over 140 enzyme reactions that support energy metabolism, cognitive function, and nervous system health.

With sustained activity throughout the day, many people experience fewer afternoon crashes, better focus, and for women, improved monthly comfort and cycle-related mood support.*

What’s the difference between the 25mg and 100mg formulas?

Both formulas use the same Complete B6 System — the difference is how much support you want.

  • ●25mg Standard Strength: Ideal for daily maintenance, general wellness, and long-term use

  • ●100mg Maximum Strength: Higher potency for more targeted support, including mood, stress, and women’s cycle wellness
Clinical studies on B6 for cycle support often use doses in the 50–100mg range, which is why some people choose the higher strength.*

How and when should I take BioActive Vitamin B6?

Take one capsule daily with food, ideally in the morning.

B6 supports neurotransmitters that influence energy and mood, so morning use helps provide steady support throughout the day.

Because BioActive B6 is designed for sustained activity, you don’t need to carefully time doses — consistency matters most.*

How long does it take to notice results?

Results develop over time with consistent use. Some people notice differences within the first few weeks, while the full benefits of sustained B6 support become more apparent with continued daily use.

B6 levels build over time, and sustained support becomes more noticeable with continued daily use.

For women using it for cycle support, tracking over 2–3 cycles can provide a clearer picture of results.*

Is BioActive Vitamin B6 safe to take?

BioActive Vitamin B6 uses P-5-P, the form your body actually uses. Because P-5-P is already active, it bypasses the conversion step that limits standard pyridoxine — meaning your body can put it to work right away. As with any supplement, if you are pregnant, nursing, taking medications, or have a medical condition, consult your healthcare provider before use.*

As with any supplement, if you are pregnant, nursing, taking medications, or have a medical condition, consult your healthcare provider before use.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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