A supplement bottle with a white cap, standing next to its matching blue and white cardboard box. The label reads "Triquetra BioActive B-Complex Max Strength." Subtext indicates it is an "Active + Methylated B Vitamin Complex" dietary supplement containing 60 capsules. The box also highlights "Cognitive, Metabolic & Energy Support" and lists vitamins B12, B9, B7, B6, B5, B3, B2, and B1.
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
BioActive Vitamin B Complex*
Triquetra BioActive B-Complex

Still not quite feeling like yourself?

BioActive B-Complex delivers active, ready-to-use B vitamins that support normal energy production, nervous system health, and a balanced mood* — in the form your body doesn’t have to convert first.
  • All-day energy, not a jolt. Active B vitamins help your body turn food into steady, usable energy — no stimulants, no c

  • Full-spectrum active B12. Methyl, Adenosyl & Hydroxo B12 — supports normal cellular energy production and nervous system function.*

  • Active, methylated forms. L-Methylfolate (5-MTHF) plus branded BenfoPure® B1 and Pantesin® B5 — forms your body uses without an extra conversion step.*

✓  Methylation-friendly · Active 5-MTHF folate

Capsules
Capsules
Liquid Drops
Liquid Drops
Select option: 180 Count
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*This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Not a substitute for medical car
Active & Methylated Forms
·
L-Methylfolate (5-MTHF)
·
Full-Spectrum Active B12
·
BenfoPure® B1 · Pantesin® B5
·
Vegan · Non-GMO
·
Third-Party Tested
·
One Capsule a Day
·
A woman at her desk with a glass of water and laptop
You might be here because—

Running low on energy, and looking for real support.

  • Your energy dips by mid-afternoon and you want steady support, not another coffee
  • You’ve tried a multivitamin or B-complex and something still isn’t quite clicking
  • You’ve heard that some people process folate differently and wondered if that applies to you
  • You’ve looked at a supplement label, seen “folic acid,” and wondered if that matters
  • You’re looking for active-form nutritional support — not a diagnosis

That’s exactly who we made this for.

From the community

Real people, real routines.

Creators and customers sharing how BioActive B-Complex fits into their day.

Individual results vary. Creators may be compensated. *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Folic acid vs. folate

“Folic acid” and “folate” are not the same thing. This one uses the active form.

Active, not synthetic

L-Methylfolate (5-MTHF) and methylcobalamin are already in the form your body uses — no extra conversion step required.*

Full-spectrum B12

Methyl, Adenosyl, and Hydroxo B12 together — supporting normal cellular energy and nervous system function.*

Branded, better-absorbed actives

BenfoPure® Benfotiamine (B1) and Pantesin® Pantethine (B5) — superior forms over standard thiamine and pantothenic acid.*

Clean & verified

All 8 B vitamins, plus choline & inositol. Vegan, non-GMO, gluten- and soy-free. Third-party tested, made in a GMP facility.

Folic acid path vs. active folate path
What’s inside

Active nutrient forms, formulated for absorption.

What’s insideHow it’s formulatedWhat it supports
Full-spectrum active B12Methyl B12, Adenosyl B12, Hydroxo B12Supports normal cellular energy production and nervous system function.*
L-Methylfolate (5-MTHF)The active form of folateAn active form of folate that supports normal cell metabolism and red blood cell formation.*
BenfoPure® B1 & Pantesin® B5Benfotiamine & PantethineBetter-absorbed forms that support normal energy metabolism.*
B2, B3, B6, B7Riboflavin, Niacin, P-5-P, BiotinRound out all 8 B vitamins that support overall metabolic health.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have a medical condition. Individual results may vary.

What it supports

Active B vitamins that support how your body actually runs.

Normal energy production

B vitamins help your body turn food into usable energy.*

Nervous system health

Support for normal nervous system function.*

Cognitive function

Support for normal cognitive function.*

Red blood cell formation

L-Methylfolate and B12 support normal red blood cell formation.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

The honest timeline

The first signs show in weeks. The steady feeling builds over months.

B vitamins support your body’s everyday processes, so the change is gradual and compounding. Here’s the honest version of what to expect.

Week 1

Start Gentle

One capsule a day, with food — especially if you know you’re sensitive to active-form B vitamins. Nothing to feel yet; you’re just setting the routine.

Weeks 2–4

It Starts Working

Most people notice a difference in here — steadier energy through the day. For some it takes longer, and that’s normal, not a sign it isn’t working.

Ongoing

Your New Normal

Taken at the same time each day, it supports your body’s normal, everyday processes.* With B vitamins, consistency matters more than dose.

A person experiencing steady energy into their routine

As with any new supplement, we recommend starting with one capsule with food — and checking with your healthcare provider first if you’re pregnant, nursing, or taking medication.

Single BioActive B-Complex capsule on white
How to take it

One capsule daily, with a meal. Morning or night — consistency is what matters.

Individual results vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Dr. Will Aguila, MD
Dr. Will Aguila, MDInternal Medicine
Dr. Nicole Avena, PhD
Dr. Nicole Avena, PhDNeuroscience & Nutrition
Dr. Dan Sullivan, ND
Dr. Dan Sullivan, NDNaturopathic Medicine
The Science Advisors

Held to a higher standard.

Independent clinicians and scientists review our formulas — not to endorse them, but to challenge them.

  • Independent oversight.Practicing clinicians and researchers review Triquetra formulas against the published evidence — on an ongoing basis, with real-world outcomes informing every cycle.
  • Reviewed against the published evidence.Every dose, form, and cofactor pairing is checked against the clinical literature. If the science doesn’t support a claim, the claim doesn’t ship.

Advisors are compensated for their time and expertise, never for endorsement.

Straight answers Questions, answered
As with any supplement — especially if you’re pregnant, nursing, taking medication, or managing a health condition — check with your healthcare provider before starting.
Everyone’s different. Some people notice a change within the first couple of weeks; others take longer.
Most people tolerate active-form B vitamins well, but individual sensitivity varies. We recommend starting with one capsule with food and adjusting from there.
No. You don’t need any testing to try active-form B vitamins. Some people simply have a gene variant that affects how their body processes folic acid, and prefer an active form.
“Folic acid” is a synthetic form used in many supplements; L-Methylfolate (5-MTHF) is an active form your body can use without an extra conversion step.*
Yes. Every batch is independently lab tested for potency and purity, and it’s made in a GMP-registered facility. Vegan, non-GMO, gluten- and soy-free.
One capsule daily, with or without food. That’s a 2-month supply per 60-count bottle.
30 DAYS
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