is a hormone naturally produced in the gut by specialized cells called L-cells. It plays a critical role in:
Appetite regulation
GLP-1 signals your brain to reduce hunger and cravings.
Gut-Brain Axis
GLP-1 is a crucial communicator between the gut and brain, helping align your body’s hunger signals with metabolic needs. This axis influences not only appetite but also overall energy balance.
Digestive efficiency
It slows the digestive process, keeping you full longer.
Unfortunately, many people have suboptimal GLP-1 levels due to factors such as poor gut health, low fiber intake, or metabolic dysfunctions.
Science now shows that nurturing your gut microbiome can naturally support GLP-1 production and activity.
How Your Gut Microbiome Affects
GLP-1 Production
Your gut is home to trillions of bacteria that produce short-chain fatty acids (SCFAs) and other metabolites essential for GLP-1 secretion. A thriving microbiome promotes:
Enhanced GLP-1 production by fueling the L-cells in your gut.
Improved gut lining health which supports the environment where GLP-1 is produced.
Balanced metabolism and reduced inflammation which optimize GLP-1 activity.
The Science Behind GLP-Complete
The Targeted Approach of GLP-Complete
Supporting your gut to create an environment optimized for GLP-1 hormone production involves three essential stages. This targeted approach works with your body’s natural processes to promote effective GLP-1 function:
‣Solnul® R2 Resistant Starch: Produces butyrate, propionate, and acetate to fuel L-cells.
‣PreticX® (XOS): Selectively nourishes beneficial bacteria like Bifidobacterium to boost
‣Beta-Glucans (from mushrooms): Ferments into SCFAs and supports gut lining repair.
GLP-Pro: Enhancing the Microbiome
‣Bifidobacterium: Stimulates SCFA production and improves gut lining health.
‣Lactobacillus: Regulates gut hormones and strengthens the gut-immune barrier.
‣Postbiotics: Active metabolites that directly fuel GLP-1 production.
GLP-Activate: Maximizing GLP-1 Efficiency
‣Phenylcapsaicin: Enhances thermogenesis and gut barrier health.
‣Curcumin: Supports anti-inflammatory pathways and gut-brain signaling.
‣Berberine: Regulates blood sugar and promotes metabolic balance.
How It Works: Supporting GLP-1 Naturally
Feeding the Gut
(GLP-Pre)
Prebiotics like resistant starch and beta-glucans ferment in the gut, creating SCFAs (butyrate, acetate, propionate). These SCFAs:
Fuel L-cells to increase GLP-1 production.
Promote growth of beneficial bacteria like
Akkermansia, which rejuvenates the gut lining.
Boosting GLP-1 Activity
(GLP-Pro)
Probiotics such as Bifidobacterium and
Lactobacillus stimulate GLP-1 by:
Producing SCFAs and other metabolites that trigger L-cell activity.
Reducing inflammation and
strengthening gut barrier integrity.
Supporting Release & Protection
(GLP-Activate)
Botanical extracts and nutrients like
EGCG (green tea extract), phenylcapsaicin,
and curcumin:
Enhance the release of GLP-1 in
response to meals.
Protect GLP-1 from rapid breakdown by
the enzyme DPP-4, extending its activity.
The Targeted Approach of GLP-Complete
Supporting your gut to create an environment optimized for GLP-1 hormone production involves three essential stages. This targeted approach works with your body’s natural processes to promote effective GLP-1 function:
Prepare the Environment
Lay the groundwork by nourishing your gut microbiome with prebiotics that fuel the L-cells and beneficial bacteria necessary for GLP-1 production.
Strengthen and Support
Enhance your gut health with probiotics and postbiotics that create a balanced environment, encouraging optimal GLP-1 secretion and reducing inflammation.
Activate and Optimize
Utilize nutrients and botanical extracts to stimulate GLP-1 release during meals, helping your body achieve and maintain peak metabolic balance.
Supporting GLP-1 production naturally offers a sustainable way to:
Reduce food cravings and emotional eating.
Enhance metabolic efficiency without drastic measures.
Improve long-term gut and overall health.
A Systemic Approach to GLP-1 Optimization
What the Research Shows
Pasteurized Akkermansia muciniphila supports metabolic health by strengthening the gut barrier, reducing inflammation, and promoting glucose control. Its membrane protein, Amuc_1100, activates TLR2 receptors, enhancing gut integrity while lowering body weight and fat mass. Additionally, it stimulates the release of GLP-1—a key hormone for satiety and glycemic balance—by activating
the GPR119 receptor through the production of 2-oleoylglycerol. When combined with targeted strategies like GLP Pro, A. muciniphila offers a natural, effective solution for achieving metabolic balance.
The L-cells in your gut play a pivotal role in managing metabolic health by secreting GLP-1. GLP-Pre’s combination of non-digestible fibers undergoes fermentation in the colon, producing key short-chain fatty acids (SCFAs) like butyrate, propionate, and acetate. These SCFAs fuel L-cells, enhancing their ability to produce and release GLP-1.
‣ Key Research: SCFAs have been shown to directly stimulate GLP-1 production while supporting overall gut barrier integrity, creating an optimal environment for metabolic regulation.
Pasteurized Akkermansia muciniphila supports metabolic health by strengthening the gut barrier, reducing inflammation, and promoting glucose control. Its membrane protein, Amuc_1100, activates TLR2 receptors, enhancing gut integrity while lowering body weight and fat mass. Additionally, it stimulates the release of GLP-1—a key hormone for satiety and glycemic balance—by activating
the GPR119 receptor through the production of 2-oleoylglycerol. When combined with targeted strategies like GLP Pro, A. muciniphila offers a natural, effective solution for achieving metabolic balance.
The L-cells in your gut play a pivotal role in managing metabolic health by secreting GLP-1. GLP-Pre’s combination of non-digestible fibers undergoes fermentation in the colon, producing key short-chain fatty acids (SCFAs) like butyrate, propionate, and acetate. These SCFAs fuel L-cells, enhancing their ability to produce and release GLP-1.
‣ Key Research: SCFAs have been shown to directly stimulate GLP-1 production while supporting overall gut barrier integrity, creating an optimal environment for metabolic regulation.
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